Class 3 semaphorin in angiogenesis and lymphangiogenesis

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Semaphorins were originally identified as axon guidance molecules involved in the development of the neuronal system. However, accumulating evidences have clearly demonstrated that the semaphorin system is not restricted to the brain but supports functions of other organs. Here, we review the rapidly emerging functions of sempahorins and, in particular class 3 semaphorin, in vascular and lymphatic systems during the development, tumor angiogenesis and ischemic revascularization.

Original languageEnglish
Pages (from-to)71-88
Number of pages18
JournalChemical Immunology and Allergy
Volume99
DOIs
Publication statusPublished - 2014

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Semaphorins
Lymphangiogenesis
Lymphatic System
Blood Vessels
Brain
Neoplasms

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

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title = "Class 3 semaphorin in angiogenesis and lymphangiogenesis",
abstract = "Semaphorins were originally identified as axon guidance molecules involved in the development of the neuronal system. However, accumulating evidences have clearly demonstrated that the semaphorin system is not restricted to the brain but supports functions of other organs. Here, we review the rapidly emerging functions of sempahorins and, in particular class 3 semaphorin, in vascular and lymphatic systems during the development, tumor angiogenesis and ischemic revascularization.",
author = "Federico Bussolino and Enrico Giraudo and Guido Serini",
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AU - Giraudo, Enrico

AU - Serini, Guido

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AB - Semaphorins were originally identified as axon guidance molecules involved in the development of the neuronal system. However, accumulating evidences have clearly demonstrated that the semaphorin system is not restricted to the brain but supports functions of other organs. Here, we review the rapidly emerging functions of sempahorins and, in particular class 3 semaphorin, in vascular and lymphatic systems during the development, tumor angiogenesis and ischemic revascularization.

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