Clear cell adenocarcinoma of the colon is a unique morphological variant of intestinal carcinoma: Case report with molecular analysis

Marta Barisella, Andrea Lampis, Federica Perrone, Antonino Carbone

Research output: Contribution to journalArticlepeer-review

Abstract

Here we report a new case of clear cell adenocarcinoma (CCA) of the colon in a 54-year-old Caucasian man. Despite of the previous reported cases, the lesion was located in the right colon and was not associated with the conventional adenoma. We performed immunohistochemical and molecular analyses in order to explore whether the CCA had the molecular features generally associated with conventional colorectal carcinoma. The immunohistochemical and molecular analyses showed that the different morphology of CCA does not reflect a distinct biological entity but only an unusual morphological variant of intestinal carcinoma.

Original languageEnglish
Pages (from-to)6575-6577
Number of pages3
JournalWorld Journal of Gastroenterology
Volume14
Issue number42
DOIs
Publication statusPublished - Nov 14 2008

Keywords

  • Beta-catenin
  • Clear cell carcinoma
  • Colon carcinoma
  • KRAS
  • Molecular analysis

ASJC Scopus subject areas

  • Gastroenterology

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