Clear cell sarcoma (malignant melanoma of soft parts) and sentinel lymph node biopsy

Franco Picciotto, Alessandro Zaccagna, Giovanni Derosa, Alberto Pisacane, Paolo Puiatti, Enrico Colombo, Fabrizio Dardano, Antonio Ottinetti

Research output: Contribution to journalArticlepeer-review


Clear cell sarcoma of the tendons and aponeuroses is an aggressive, rare soft tissue tumour that occurs predominantly in the extremities of young adults. Although it appears to be histogenetically related to melanoma, its clinical behaviour resembles soft tissue sarcoma. Prognosis is reported to be poor due to the great propensity of regional and distant metastases. The risk of metastases to regional lymph nodes is very high. We describe a case of clear cell sarcoma of the hand and evaluate the feasibility of the sentinel lymph node biopsy (SLNB) technique in this kind of tumour. Up to now, there are no reports that describe the use of SLNB in clear cell sarcoma. The SLNB technique was carried out with success and the sentinel lymphnode was easily identified. Histological examination of the lymphnode allowed identification of metastatic cells and thus provide for radical lymphadenectomy. We maintain that SLNB can be successfully used for this type of tumour although this result should be evaluated and confirmed by larger case studies.

Original languageEnglish
Pages (from-to)46-48
Number of pages3
JournalEuropean Journal of Dermatology
Issue number1
Publication statusPublished - Jan 2005


  • Clear cell
  • Melanoma
  • Sarcoma
  • Sentinel node biopsy

ASJC Scopus subject areas

  • Dermatology


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