Abstract
A human immunodeficiency virus-negative woman with severe classic Kaposi's sarcoma, idiopathic leukopenia, and massive spread of human herpesvirus 8 (HHV-8) in circulating cells showed stable disease remission in response to systemic interferon-α treatment that was accompanied by increased CD3+ and CD4+ T cell numbers and complete clearance of HHV-8 from the circulation. These results suggest a direct relationship between HHV-8 clearance from blood and regression of Kaposi's sarcoma and are consistent with the in vitro inhibitory effects of interferon-α on HHV-8 infection.
Original language | English |
---|---|
Pages (from-to) | 1782-1785 |
Number of pages | 4 |
Journal | Clinical Infectious Diseases |
Volume | 33 |
Issue number | 10 |
DOIs | |
Publication status | Published - Nov 15 2001 |
ASJC Scopus subject areas
- Immunology