Clinical and angiographic correlates of dobutamine-induced wall motion patterns after myocardial infarction

Riccardo Bigi, Lauro Cortigiani, Alessandro Desideri, Paola Colombo, Carlo Sponzilli, Jeroen J. Bax, Cesare Fiorentini

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The ability of different dobutamine-induced wall motion patterns to define the anatomic status of the infarct-related artery (IRA) was evaluated in 159 patients who underwent dobutamine stress echocardiography (DSE) and coronary angiography 10 ± 2 and 18 ± 3 days, respectively, after hospital admission. The DSE result was classified as: (1) biphasic: improvement with a low dose followed by deterioration with a high dose; (2) worsening: direct deterioration at low or high doses; (3) sustained improvement: improvement with a low dose that was maintained at high dose; and (4) no change: no change during the entire protocol. A diameter narrowing >70% (50% for the left main stem) of major coronary arteries indicated a severe lesion. Angiograms were classified according to the jeopardy score and collateral circulation graded according to Rentrop's classification. DSE was positive in 92 patients (22 had biphasic results and 70 had worsening results) and negative in 67 patients (14 had sustained improvement and 53 had no changes). Biphasic response was associated with more frequent anterior infarction (p

Original languageEnglish
Pages (from-to)944-948
Number of pages5
JournalThe American Journal of Cardiology
Issue number9
Publication statusPublished - Nov 1 2001


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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