Clinical and angiographic outcome after coronary arterial stenting with the carbostent

David Antoniucci, Antonio Bartorelli, Renato Valenti, Piero Montorsi, Giovanni M. Santoro, Franco Fabbiocchi, Leonardo Bolognese, Alessandro Loaldi, Maurizio Trapani, Daniela Trabattoni, Guia Moschi, Stefano Galli

Research output: Contribution to journalArticlepeer-review


The Carbostent is a new balloon-expandable, stainless steel, tubular stent with innovative multicellular design and unique turbostratic carbon coating (Carbofilm). This open nonrandomized 2-center study assesses the immediate and long-term clinical and angiographic outcomes after Carbostent implantation in patients with native coronary artery disease. The Carbostent was implanted in 112 patients with 132 de novo lesions. Most patients (55%) had unstable angina, and 38% of lesions were type B2-C. The mean lesion length was 12.5 ± 7.0 mm, and 29% of lesions were >15 mm in length. No stent deployment failure occurred, as well as acute or subacute stent thrombosis. The 6-month event-free survival was 84 ± 4%. One patient with a stented right coronary artery and no restenosis at the angiographic follow-up died after 6 months of fatal infarction due to abrupt closure of a nontarget vessel. In-hospital non-Q-wave myocardial infarction occurred in 1 patient, and 11 patients had repeat target lesion revascularization (target lesion revascularization rate 10%). The 6-month angiographic follow-up was obtained in 108 patients (96%) (127 lesions). Angiographic restenosis rate was 11%. The loss index was 0.29 ± 0.28. The results of this study indicate a potential benefit of Carbostent for the prevention of stent thrombosis and restenosis in these relatively high-risk patients. A larger trial is being planned to confirm these promising results. Copyright (C) 2000 Excerpta Medica Inc.

Original languageEnglish
Pages (from-to)821-825
Number of pages5
JournalThe American Journal of Cardiology
Issue number7
Publication statusPublished - Apr 1 2000

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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