Clinical and angiographic outcomes after percutaneous recanalization of chronic total saphenous vein graft occlusion using modern techniques

Rasha Al-Lamee, Alfonso Ielasi, Azeem Latib, Cosmo Godino, Massimo Ferraro, Francesco Arioli, Marco Mussardo, Daniela Piraino, Filippo Figini, Mauro Carlino, Matteo Montorfano, Alaide Chieffo, Antonio Colombo

Research output: Contribution to journalArticle

Abstract

Poor long-term outcomes after percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) of saphenous vein grafts (SVGs) have been reported. However, limited data are available evaluating the use of modern techniques in this group. The aim of the present study was to assess the efficacy and long-term outcomes of PCI in SVG CTO with the routine use of embolic protection devices and drug-eluting stents. A retrospective cohort analysis was conducted of all consecutive patients undergoing PCI to SVG CTO from May 2002 to July 2009 at 2 centers. The indication for PCI was the presence of angina or silent ischemia with evidence of inducible ischemia after functional testing in the territory supplied by the SVG, despite optimal medical therapy. We identified 34 patients with SVG CTO. Of the 34 patients, 23 (68%) underwent successful SVG recanalization with stent implantation. An embolic protection device was used in 78% and 95% of stents implanted were drug-eluting stents. No in-hospital major adverse cardiac events occurred in the successful PCI group; one myocardial infarction occurred in the unsuccessful group. At follow-up (median 18.0 months, interquartile range 10.4 to 48.3), 1 case of myocardial infarction had occurred in the successful group. The in-stent restenosis rate was 68% (n = 13), of which 77% were focal, with target vessel revascularization in 61%. In conclusion, despite the relatively low procedural success rates, the clinical outcomes after successful PCI to SVG CTO with modern techniques were favorable. The repeat revascularization rates were high; however, graft patency was achievable in most after reintervention.

Original languageEnglish
Pages (from-to)1721-1727
Number of pages7
JournalThe American Journal of Cardiology
Volume106
Issue number12
DOIs
Publication statusPublished - Dec 15 2010

Fingerprint

Saphenous Vein
Percutaneous Coronary Intervention
Transplants
Embolic Protection Devices
Stents
Drug-Eluting Stents
Ischemia
Myocardial Infarction
Cohort Studies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Clinical and angiographic outcomes after percutaneous recanalization of chronic total saphenous vein graft occlusion using modern techniques. / Al-Lamee, Rasha; Ielasi, Alfonso; Latib, Azeem; Godino, Cosmo; Ferraro, Massimo; Arioli, Francesco; Mussardo, Marco; Piraino, Daniela; Figini, Filippo; Carlino, Mauro; Montorfano, Matteo; Chieffo, Alaide; Colombo, Antonio.

In: The American Journal of Cardiology, Vol. 106, No. 12, 15.12.2010, p. 1721-1727.

Research output: Contribution to journalArticle

Al-Lamee, Rasha ; Ielasi, Alfonso ; Latib, Azeem ; Godino, Cosmo ; Ferraro, Massimo ; Arioli, Francesco ; Mussardo, Marco ; Piraino, Daniela ; Figini, Filippo ; Carlino, Mauro ; Montorfano, Matteo ; Chieffo, Alaide ; Colombo, Antonio. / Clinical and angiographic outcomes after percutaneous recanalization of chronic total saphenous vein graft occlusion using modern techniques. In: The American Journal of Cardiology. 2010 ; Vol. 106, No. 12. pp. 1721-1727.
@article{671716ca9879477d9d32ebcbc4d4dfce,
title = "Clinical and angiographic outcomes after percutaneous recanalization of chronic total saphenous vein graft occlusion using modern techniques",
abstract = "Poor long-term outcomes after percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) of saphenous vein grafts (SVGs) have been reported. However, limited data are available evaluating the use of modern techniques in this group. The aim of the present study was to assess the efficacy and long-term outcomes of PCI in SVG CTO with the routine use of embolic protection devices and drug-eluting stents. A retrospective cohort analysis was conducted of all consecutive patients undergoing PCI to SVG CTO from May 2002 to July 2009 at 2 centers. The indication for PCI was the presence of angina or silent ischemia with evidence of inducible ischemia after functional testing in the territory supplied by the SVG, despite optimal medical therapy. We identified 34 patients with SVG CTO. Of the 34 patients, 23 (68{\%}) underwent successful SVG recanalization with stent implantation. An embolic protection device was used in 78{\%} and 95{\%} of stents implanted were drug-eluting stents. No in-hospital major adverse cardiac events occurred in the successful PCI group; one myocardial infarction occurred in the unsuccessful group. At follow-up (median 18.0 months, interquartile range 10.4 to 48.3), 1 case of myocardial infarction had occurred in the successful group. The in-stent restenosis rate was 68{\%} (n = 13), of which 77{\%} were focal, with target vessel revascularization in 61{\%}. In conclusion, despite the relatively low procedural success rates, the clinical outcomes after successful PCI to SVG CTO with modern techniques were favorable. The repeat revascularization rates were high; however, graft patency was achievable in most after reintervention.",
author = "Rasha Al-Lamee and Alfonso Ielasi and Azeem Latib and Cosmo Godino and Massimo Ferraro and Francesco Arioli and Marco Mussardo and Daniela Piraino and Filippo Figini and Mauro Carlino and Matteo Montorfano and Alaide Chieffo and Antonio Colombo",
year = "2010",
month = "12",
day = "15",
doi = "10.1016/j.amjcard.2010.08.013",
language = "English",
volume = "106",
pages = "1721--1727",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "12",

}

TY - JOUR

T1 - Clinical and angiographic outcomes after percutaneous recanalization of chronic total saphenous vein graft occlusion using modern techniques

AU - Al-Lamee, Rasha

AU - Ielasi, Alfonso

AU - Latib, Azeem

AU - Godino, Cosmo

AU - Ferraro, Massimo

AU - Arioli, Francesco

AU - Mussardo, Marco

AU - Piraino, Daniela

AU - Figini, Filippo

AU - Carlino, Mauro

AU - Montorfano, Matteo

AU - Chieffo, Alaide

AU - Colombo, Antonio

PY - 2010/12/15

Y1 - 2010/12/15

N2 - Poor long-term outcomes after percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) of saphenous vein grafts (SVGs) have been reported. However, limited data are available evaluating the use of modern techniques in this group. The aim of the present study was to assess the efficacy and long-term outcomes of PCI in SVG CTO with the routine use of embolic protection devices and drug-eluting stents. A retrospective cohort analysis was conducted of all consecutive patients undergoing PCI to SVG CTO from May 2002 to July 2009 at 2 centers. The indication for PCI was the presence of angina or silent ischemia with evidence of inducible ischemia after functional testing in the territory supplied by the SVG, despite optimal medical therapy. We identified 34 patients with SVG CTO. Of the 34 patients, 23 (68%) underwent successful SVG recanalization with stent implantation. An embolic protection device was used in 78% and 95% of stents implanted were drug-eluting stents. No in-hospital major adverse cardiac events occurred in the successful PCI group; one myocardial infarction occurred in the unsuccessful group. At follow-up (median 18.0 months, interquartile range 10.4 to 48.3), 1 case of myocardial infarction had occurred in the successful group. The in-stent restenosis rate was 68% (n = 13), of which 77% were focal, with target vessel revascularization in 61%. In conclusion, despite the relatively low procedural success rates, the clinical outcomes after successful PCI to SVG CTO with modern techniques were favorable. The repeat revascularization rates were high; however, graft patency was achievable in most after reintervention.

AB - Poor long-term outcomes after percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) of saphenous vein grafts (SVGs) have been reported. However, limited data are available evaluating the use of modern techniques in this group. The aim of the present study was to assess the efficacy and long-term outcomes of PCI in SVG CTO with the routine use of embolic protection devices and drug-eluting stents. A retrospective cohort analysis was conducted of all consecutive patients undergoing PCI to SVG CTO from May 2002 to July 2009 at 2 centers. The indication for PCI was the presence of angina or silent ischemia with evidence of inducible ischemia after functional testing in the territory supplied by the SVG, despite optimal medical therapy. We identified 34 patients with SVG CTO. Of the 34 patients, 23 (68%) underwent successful SVG recanalization with stent implantation. An embolic protection device was used in 78% and 95% of stents implanted were drug-eluting stents. No in-hospital major adverse cardiac events occurred in the successful PCI group; one myocardial infarction occurred in the unsuccessful group. At follow-up (median 18.0 months, interquartile range 10.4 to 48.3), 1 case of myocardial infarction had occurred in the successful group. The in-stent restenosis rate was 68% (n = 13), of which 77% were focal, with target vessel revascularization in 61%. In conclusion, despite the relatively low procedural success rates, the clinical outcomes after successful PCI to SVG CTO with modern techniques were favorable. The repeat revascularization rates were high; however, graft patency was achievable in most after reintervention.

UR - http://www.scopus.com/inward/record.url?scp=78649699254&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649699254&partnerID=8YFLogxK

U2 - 10.1016/j.amjcard.2010.08.013

DO - 10.1016/j.amjcard.2010.08.013

M3 - Article

C2 - 21126616

AN - SCOPUS:78649699254

VL - 106

SP - 1721

EP - 1727

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 12

ER -