Clinical and biological markers in gastric cancer: Update and perspectives

Alessandro Cappellani, Antonio Zanghi, Maria Di Vita, Ernesto Zanet, Pierfrancesco Veroux, Bruno Cacopardo, Andrea Cavallaro, Gaetano Piccolo, Emanuele Lo Menzo, Paolo Murabito, Massimiliano Berretta

Research output: Contribution to journalArticlepeer-review

Abstract

Gastric cancer is the second cause of death from cancer worldwide and the only chance to reach better outcomes lays on an early diagnosis. The need for non-invasive, low-cost tests is invoked also in countries in which imaging and endoscopic screening have already showed the ability to improve early diagnosis and overall survival. Genomic medicine could allow a better understanding of regulatory pathways driving the development and growth of gastric cancer and the characterization of specific molecular targets actually stimulate new drug developments. The knowledge of the role of Helicobacter pylori (HP) in gastric tumor pathogenesis has put new insides in the understanding of this peculiar disease and enriched the field of gastric biomarkers.

Original languageEnglish
Pages (from-to)403-412
Number of pages10
JournalFrontiers in Bioscience - Scholar
Volume2 S
Issue number2
Publication statusPublished - Jan 1 2010

Keywords

  • Follow up
  • Gastric cancer
  • Markers
  • Metastasis
  • Review
  • Screening

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Medicine(all)

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