Clinical and cognitive correlates of visual hallucinations in dementia with Lewy bodies

Annachiara Cagnin, Francesca Gnoato, Nela Jelcic, Silvia Favaretto, Giulia Zarantonello, Mario Ermani, Mauro Dam

Research output: Contribution to journalArticlepeer-review


Background: The presence of recurrent complex visual hallucinations (VHs) is a core feature of dementia with Lewy bodies (DLB). The aim of this study was to investigate which clinical and neuropsychological characteristics are associated with VHs and their predictive value over a 1 year follow-up. Methods 81 DLB patients, 41 with (VH+) and 36 without (VH-) VHs, and 45 patients with Alzheimer's disease (AD), were enrolled. All participants underwent extensive neuropsychological testing. Visual-spatial and perceptual abilities were evaluated with the Visual and Object Space Perception (VOSP) battery. Fluctuations in attention, rapid eye movement sleep behaviour disorder (RBD) symptoms, extrapyramidal signs and behavioural disturbances were studied with dedicated clinical scales. Results: The presence of VHs was associated with older age and later disease onset, but not with disease duration or with fluctuations, RBD or parkinsonism severity. Cognitive correlates of VHs were deficits in visual attention (digit cancellation: p

Original languageEnglish
Pages (from-to)505-510
Number of pages6
JournalJournal of Neurology, Neurosurgery and Psychiatry
Issue number5
Publication statusPublished - May 2013

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Surgery
  • Arts and Humanities (miscellaneous)


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