TY - JOUR
T1 - Clinical and electrocardiographic features and long-term results of electrical therapy in patients with isolated His bundle disease
AU - Mangiardi, Lucia M.
AU - Ronzani, Giuliana
AU - Gaita, Fiorenzo
AU - Presbitero, Patrizia
AU - Conte, Maria Rosa
AU - Di Leo, Margherita
AU - Commodo, Enzo
AU - Brusca, Antonio
PY - 1986
Y1 - 1986
N2 - The clinical, ECG, and electrophysiologic findings of 35 consecutive patients with second- and third-degree intra-His block with normal QRS complexes were examined. The follow-up period varied between 12 and 120 months (mean 45). Seventy-seven per cent of the patients were women. Underlying heart disease was present in 43% of the patients. ECGs were characterized by both second-degree type I and type II atrioventricular block, normal or slightly prolonged PR interval of the conducted beats or of the first conducted beat of a Wenckebach sequence, and by subtle changes in the initial forces of the QRS complexes of the escape beats. Electrophysiologic study showed normal sinus and atrioventricular node function and normal infra-His conduction in all patients. In four patients repetitive bradycardia-dependent intra-His block was induced. Thirty-two patients were permanently paced soon after the initial evaluation and three during the follow-up period. Total long-term mortality rate was 23%. None of the patients developed bundle branch block.
AB - The clinical, ECG, and electrophysiologic findings of 35 consecutive patients with second- and third-degree intra-His block with normal QRS complexes were examined. The follow-up period varied between 12 and 120 months (mean 45). Seventy-seven per cent of the patients were women. Underlying heart disease was present in 43% of the patients. ECGs were characterized by both second-degree type I and type II atrioventricular block, normal or slightly prolonged PR interval of the conducted beats or of the first conducted beat of a Wenckebach sequence, and by subtle changes in the initial forces of the QRS complexes of the escape beats. Electrophysiologic study showed normal sinus and atrioventricular node function and normal infra-His conduction in all patients. In four patients repetitive bradycardia-dependent intra-His block was induced. Thirty-two patients were permanently paced soon after the initial evaluation and three during the follow-up period. Total long-term mortality rate was 23%. None of the patients developed bundle branch block.
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U2 - 10.1016/0002-8703(86)90347-9
DO - 10.1016/0002-8703(86)90347-9
M3 - Article
C2 - 3788765
AN - SCOPUS:0022974225
VL - 112
SP - 1183
EP - 1191
JO - American Heart Journal
JF - American Heart Journal
SN - 0002-8703
IS - 6
ER -