Abstract
In a study of 37 patients with hepatitis C (proved histologically) positive chronic hepatitis, a correlation was seen between clinical efficacy and histological improvement after treatment with interferon alfa-2b (3 million units (MU) three times a week for six months plus six months' follow up). Alanine aminotransferase activities became normal in 18 (48%) patients during treatment; at the end of follow up eight (45%) had a continued response to the treatment. Paired liver biopsy specimens showed marked improvements in Knodell index score and portal inflammation in these patients.
| Original language | English |
|---|---|
| Journal | Gut |
| Volume | 34 |
| Issue number | 2 SUPPL |
| DOIs | |
| Publication status | Published - 1993 |
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ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Gastroenterology
Cite this
Clinical and histological evaluation of interferon alfa-2b in the treatment of chronic hepatitis C. / Panella, C.; Francavilla, A.; Conte, D.; Tatulli, I.; Rubini, F.
In: Gut, Vol. 34, No. 2 SUPPL, 1993.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical and histological evaluation of interferon alfa-2b in the treatment of chronic hepatitis C
AU - Panella, C.
AU - Francavilla, A.
AU - Conte, D.
AU - Tatulli, I.
AU - Rubini, F.
PY - 1993
Y1 - 1993
N2 - In a study of 37 patients with hepatitis C (proved histologically) positive chronic hepatitis, a correlation was seen between clinical efficacy and histological improvement after treatment with interferon alfa-2b (3 million units (MU) three times a week for six months plus six months' follow up). Alanine aminotransferase activities became normal in 18 (48%) patients during treatment; at the end of follow up eight (45%) had a continued response to the treatment. Paired liver biopsy specimens showed marked improvements in Knodell index score and portal inflammation in these patients.
AB - In a study of 37 patients with hepatitis C (proved histologically) positive chronic hepatitis, a correlation was seen between clinical efficacy and histological improvement after treatment with interferon alfa-2b (3 million units (MU) three times a week for six months plus six months' follow up). Alanine aminotransferase activities became normal in 18 (48%) patients during treatment; at the end of follow up eight (45%) had a continued response to the treatment. Paired liver biopsy specimens showed marked improvements in Knodell index score and portal inflammation in these patients.
UR - http://www.scopus.com/inward/record.url?scp=0027314046&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027314046&partnerID=8YFLogxK
U2 - 10.1136/gut.34.2_Suppl.S127
DO - 10.1136/gut.34.2_Suppl.S127
M3 - Article
C2 - 8314478
AN - SCOPUS:0027314046
VL - 34
JO - Gut
JF - Gut
SN - 0017-5749
IS - 2 SUPPL
ER -