Abstract
In a study of 37 patients with hepatitis C (proved histologically) positive chronic hepatitis, a correlation was seen between clinical efficacy and histological improvement after treatment with interferon alfa-2b (3 million units (MU) three times a week for six months plus six months' follow up). Alanine aminotransferase activities became normal in 18 (48%) patients during treatment; at the end of follow up eight (45%) had a continued response to the treatment. Paired liver biopsy specimens showed marked improvements in Knodell index score and portal inflammation in these patients.
Original language | English |
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Journal | Gut |
Volume | 34 |
Issue number | 2 SUPPL |
DOIs | |
Publication status | Published - 1993 |
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Gastroenterology