Clinical and instrumental evaluation of the activity of an anti-wrinkle cosmetic product on cutaneous relief and photoaged skin

E. Berardesca, F. Distante, P. Anthoine, G. Rabbiosi, L. Aubert

Research output: Contribution to journalArticle


The aim of this trial is to evaluate the efficacy of an anti-wrinkle cosmetic product on the cutaneous relief and condition of photoaged skin using a method of clinical scores together with an instrumental technique, namely image analysis of imprints taken from the crow's feet area of the eye. Thirty women presenting with cutaneous photoaging of the face applied the product twice daily for two months. Skin condition was evaluated before treatment (DO) and after 15, 30 and 60 days of treatment (D15, D30 and D60). Safety was verified at each visit. Progressive and significant improvement in cutaneous relief and the state of the skin was found, which was identical by both methods of measurement, thereby confirming the value of the clinical score method.

Original languageEnglish
Pages (from-to)69-75
Number of pages7
JournalJournal of Applied Cosmetology
Issue number2
Publication statusPublished - 1997



  • Image analysis
  • Replica
  • Wrinkles

ASJC Scopus subject areas

  • Dermatology

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