Clinical and laboratory evaluations in 348 chronic urticaria patients

Paolo D. Pigatto, Rossano H. Valsecchi

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Background: chronic urticaria may be due to various causes and frequently does not have a single aetiology. We designed this paper to present the results of a study conducted at the Departments of Dermatology of Milan and Bergamo when patients with chronic urticaria are examined. Materials and methods: 348 patients underwent a protocol consisting of the recording of their pathological history and objective signs of the episode, their personal and family history of allergies, and the performance of laboratory and instrumental diagnostic tests. Results: there were several positive test results (thus indicating more than one possible factor in many of the patients), but their relevance was very low. These included high eosinophil counts, increased IgE levels and a high number of positive Helicobacter pylori antibodies (with very little relevance), good responses to allergen and pseudo allergen- free diet; only a few patients had turnouts or vital diseases. Conclusions: the real problem of chronic urticaria lies in the fact that no main causative factors can be detected, except possibly an inherited predisposition to atopic 'allergic' skin reactivity. The data concerning specifically related affections (food and/or dust mite allergies, intestinal parasitic infestations caused by Giardia and the presence of Helicobacter pylori gastric disturbances) are limited to some selected cases and have little real relevance.

Original languageEnglish
Pages (from-to)13-18
Number of pages6
JournalAnnali Italiani di Dermatologia Allergologica Clinica e Sperimentale
Issue number1
Publication statusPublished - Jan 2000


  • Chronic urticaria
  • Diagnostic protocol
  • Relevance

ASJC Scopus subject areas

  • Dermatology


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