TY - JOUR
T1 - Clinical and molecular observations of two fatal cases of rotavirus-associated enteritis in children in Italy
AU - Medici, Maria Cristina
AU - Abelli, Laura Anna
AU - Martinelli, Monica
AU - Corradi, Domenico
AU - Dodi, Icilio
AU - Tummolo, Fabio
AU - Albonetti, Valeria
AU - Martella, Vito
AU - Dettori, Giuseppe
AU - Chezzi, Carlo
PY - 2011/7
Y1 - 2011/7
N2 - Two fatal cases of infantile rotavirus enteritis occurred in northern Italy in 2005. Both children were severely dehydrated, and death was related to severe cerebral edema. Histological examination demonstrated extensive damage of the intestinal epithelium, villous atrophy or blunting, and macrophage infiltration. The two rotavirus strains were of the G1P[8] type and the long electropherotype. The 2005 G1P[8] rotaviruses differed in the NSP4, VP3, VP4, and VP7 genes from G1P[8] rotaviruses circulating in 2004, suggesting the onset of a new G1P[8] strain in the local population.
AB - Two fatal cases of infantile rotavirus enteritis occurred in northern Italy in 2005. Both children were severely dehydrated, and death was related to severe cerebral edema. Histological examination demonstrated extensive damage of the intestinal epithelium, villous atrophy or blunting, and macrophage infiltration. The two rotavirus strains were of the G1P[8] type and the long electropherotype. The 2005 G1P[8] rotaviruses differed in the NSP4, VP3, VP4, and VP7 genes from G1P[8] rotaviruses circulating in 2004, suggesting the onset of a new G1P[8] strain in the local population.
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U2 - 10.1128/JCM.01358-10
DO - 10.1128/JCM.01358-10
M3 - Article
C2 - 21525221
AN - SCOPUS:79959822115
VL - 49
SP - 2733
EP - 2739
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 7
ER -