Clinical and MRI assessment of disease activity in patients with multiple sclerosis after influenza vaccination

Marco Salvetti, Angela Pisani, Stefano Bastianello, Enrico Millefiorini, Carla Buttinelli, Carlo Pozzilli

Research output: Contribution to journalArticle

Abstract

We investigated the possible effects of influenza vaccinationon disease activity in multiple sclerosis (MS). Six patients were evaluated clinically during the year preceding and the year following influenza vaccination. Gadolinium-enhanced magnetic resonance imaging (Gd-MRI) was performed one day before and at days 15 and 45 after vaccination. Cumulatively, we did not observe increases in clinical or MRI disease activity following vaccination, with the exception of one case. This was the patient with the highest clinical disease activity during the year preceding vaccination. These results support and supplement previous observations, indicating that influenza vaccination is a safe procedure in multiple sclerosis. Nevertheless, it should be used with caution in patients with active/progressing disease.

Original languageEnglish
Pages (from-to)143-146
Number of pages4
JournalJournal of Neurology
Volume242
Issue number3
DOIs
Publication statusPublished - Mar 1995

Keywords

  • Magnetic resonance imaging
  • Multiple sclerosis
  • Vaccination

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Clinical and MRI assessment of disease activity in patients with multiple sclerosis after influenza vaccination'. Together they form a unique fingerprint.

  • Cite this