A series of 24 children with cerbrovascular occlusive disease is presented. In all but one case severe or very severe neurological deficits were present upon admission. Epilepsy was associated with the onset of the symptoms in 9 cases. The angiographic lesions were located, in most cases, in the vicinity of the anterior part of the circle of Willis, involving the middle cerebral artery alone in 5 cases or multiple intracranial vessels in 8 cases. The incidence of Moya-Moya disease was quite relevant (5 cases). In all of these three angiographic groups, CT scanning follow-up studies revealed very severe anatomical brain damage. Brain hemiatrophy was observed in about 60% of all the cases. In spite of these similarities, Moya-Moya disease appeared to have a more unfavourable clinical course (occurrence of repeated ischemic events, high incidence of epileptic seizures, severe residual disability often requiring special assistance) leading to the final conclusion that extra-intracranial arterial by-pass surgery may be advisable in these cases.
|Number of pages||2|
|Journal||Zeitschrift fur Kinderchirurgie|
|Publication status||Published - 1981|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health