Utilità clinica e prognostica della determinazione del ki67 nel carcinoma mammario.

Translated title of the contribution: Clinical and prognostic usefulness of Ki67 determination in breast carcinoma

O. Gottardi, D. Tabiadon, F. Scanzi, A. Bono, M. Majno, M. Ferrari, P. Colombo

Research output: Contribution to journalArticlepeer-review

Abstract

We studied the correlation between tumor size, nodal status, menopausal status, nuclear oestrogen receptors, disease free survival and Ki67 (proliferation rate) measured by mean of immunohistochemical analysis with monoclonal antibody. Median value was 10%. From December 1986 to October 1989 we studied 236 consecutive patients (pts). Median follow up was 34 months (range 7-51 months). Median age was 56 years (r. 26-82). We observed: 1) lower levels in smaller tumors; 2) poor correlation with nodes involvement; 3) lower levels when nuclear oestrogen receptors were positive. Preliminary data seem to suggest longer disease free survival when Ki67 is low.

Translated title of the contributionClinical and prognostic usefulness of Ki67 determination in breast carcinoma
Original languageItalian
Pages (from-to)15-22
Number of pages8
JournalPathologica
Volume84
Issue number1094
Publication statusPublished - Nov 1992

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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