Clinical and video-polygraphic features of epileptic spasms in adults with cortical migration disorder

Angelina Cerullo, Carla Marini, Roberta Carcangiu, Agostino Baruzzi, Paolo Tinuper

Research output: Contribution to journalArticlepeer-review


The International Classification of Epileptic Syndromes considers epileptic spasms to be typical seizures of West syndrome. Literature reports show that spasms are present in epileptic syndromes other than West syndrome but there are few data on their characteristics in adults. We describe ictal, clinical and video-polygraphic findings in three patients (aged 21, 32 and 57 years) with epileptic spasms and with diffuse (case 2), focal right fronto-parietal (case 1) and bi-opercular (case 3) pachygyria. Spasms had been present since the ages of 1 month, 11 and 27 years respectively. Only one patient is mentally retarded. Two of our patients (cases 2 and 3) have partial seizures. Ictal polygraphic studies showed a positive, diffuse, high amplitude slow wave activity during spasms, with superimposed fast activity, followed by a diffuse flattening in all cases with a typical muscle pattern. Epileptic spasms, as typically described in West syndrome, can maintain the same semeiological and electroencephalographic features during adulthood in certain patients with cortical dysplasia.

Original languageEnglish
Pages (from-to)27-33
Number of pages7
JournalEpileptic Disorders
Issue number1
Publication statusPublished - 1999


  • Cortical migration disorder
  • Epileptic spasms
  • Semiology
  • Video-polygraphy

ASJC Scopus subject areas

  • Clinical Neurology


Dive into the research topics of 'Clinical and video-polygraphic features of epileptic spasms in adults with cortical migration disorder'. Together they form a unique fingerprint.

Cite this