Impiego clinico della sequenza RM di perfusione con tecnica dinamica contrastografica nei tumori cerebrali

Translated title of the contribution: Clinical applications of dynamic susceptibility contrast perfusionweighted MR imaging in brain tumours

A. Romano, M. C. Rossi Espagnet, L. F. Calabria, V. Coppola, L. Figà Talamanca, V. Cipriani, G. Minniti, A. Pierallini, L. M. Fantozzi, A. Bozzao

Research output: Contribution to journalArticlepeer-review

Abstract

Magnetic resonance imaging (MRI) with a dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) sequence to study brain tumours provides information on the haemodynamic characteristics of the neoplastic tissue. Brain perfusion maps and calculation of perfusion parameters, such as relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV) and mean transit time (MTT) allow assessment of vascularity and angiogenesis within tumours of the central nervous system (CNS), thus providing additional information to conventional MRI sequences. Although DSC-PWI has long been used, its clinical use in the study of brain tumours in daily clinical practice is still to be defined. The aim of this review was to analyse the application of perfusion MRI in the study of brain tumours by summarising our personal experience and the main results reported in the literature.

Translated title of the contributionClinical applications of dynamic susceptibility contrast perfusionweighted MR imaging in brain tumours
Original languageItalian
Pages (from-to)445-460
Number of pages16
JournalRadiologia Medica
Volume117
Issue number3
DOIs
Publication statusPublished - Apr 2012

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

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