Clinical, biochemical and histological abnormalities in adult celiac patients on gluten-free diet

M. T. Bardella, N. Molteni, M. Quatrini, P. Velio, T. Ranzi, P. A. Bianchi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Twenty-six adult patients with histologically confirmed celiac disease on gluten-free diet after apparent disease remission were reexamined at 4-6 month intervals for a mean period of 55.4 months (range 13-137). Eight patients remained clinically well with normal blood tests. Eighteen patients had clinical or biological abnormalities. Eleven patients reported repeated episodes of meteorism and abdominal pain and/or diarrhea which disappeared in 2 after lactose withdrawal. Iron deficiency and macrocytic anemia were sometimes observed in 5 and 4 patients respectively. Altered plasma calcium, phosphorus and alkaline phosphatase and/or bone densitometry findings were detected in 7 patients. Seventeen patients (12 presenting some of the above findings) agreed to a repeat biopsy: 13 of these showed grade II and 4 grade III abnormalities. Although adult celiac patients may show marked improvement during gluten-free diet, minor clinical disturbances and biochemical abnormalities may still be present.

Original languageEnglish
Pages (from-to)787-789
Number of pages3
JournalGastroenterologie Clinique et Biologique
Volume9
Issue number11
Publication statusPublished - 1985

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Gluten-Free Diet
Abdomen
Macrocytic Anemia
Iron-Deficiency Anemias
Densitometry
Hematologic Tests
Celiac Disease
Lactose
Phosphorus
Abdominal Pain
Alkaline Phosphatase
Diarrhea
Calcium
Biopsy
Bone and Bones

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Bardella, M. T., Molteni, N., Quatrini, M., Velio, P., Ranzi, T., & Bianchi, P. A. (1985). Clinical, biochemical and histological abnormalities in adult celiac patients on gluten-free diet. Gastroenterologie Clinique et Biologique, 9(11), 787-789.

Clinical, biochemical and histological abnormalities in adult celiac patients on gluten-free diet. / Bardella, M. T.; Molteni, N.; Quatrini, M.; Velio, P.; Ranzi, T.; Bianchi, P. A.

In: Gastroenterologie Clinique et Biologique, Vol. 9, No. 11, 1985, p. 787-789.

Research output: Contribution to journalArticle

Bardella, MT, Molteni, N, Quatrini, M, Velio, P, Ranzi, T & Bianchi, PA 1985, 'Clinical, biochemical and histological abnormalities in adult celiac patients on gluten-free diet', Gastroenterologie Clinique et Biologique, vol. 9, no. 11, pp. 787-789.
Bardella, M. T. ; Molteni, N. ; Quatrini, M. ; Velio, P. ; Ranzi, T. ; Bianchi, P. A. / Clinical, biochemical and histological abnormalities in adult celiac patients on gluten-free diet. In: Gastroenterologie Clinique et Biologique. 1985 ; Vol. 9, No. 11. pp. 787-789.
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