Introduction: The house dust mite allergy represents the most frequent cause of airway hypersensitivity in children under 6 years and one of the main up to 18 years. In the field of the allergy to dust mites, after the specific immunotherapy (SIT), at the moment the most effective way to prevent and/or lessen the severity of this disease is reducing the house dust mite allergen levels by environmental procedures. We evaluated the efficacy of ultrasonic revulsion in children with intermittent or mild persistent asthma, allergic to dust mites. Materials and methods: Fourty children (27 M, 13 F, average age 6.5 years, range 4-15.5 years) were included in a prospectic, randomized, double blind study of an expected 6 months lenght, by receiving undistinguishable devices, working or disactivated. Daily clinic diaries, returned at the monthly checks, revealed the number of episodes of dyspnoea, wheezing, nasal obstruction, itchiness, rhinorrea, sneezes, night and exercise-induced cough. The collected data have been submitted to statistic analysis by Student test. Results: The survey has been suspended at the fourth month having reached statistical significance. All the patients have completed the survey. The first month of the treatment didn't show any significant statistics differences. In the second month significant differences related to 4/8 symptoms (nasal obstruction, sneezes, itchiness and rhinorrea) have been revealed. Only 2 symptoms (nasal obstruction and wheezing) were different between the 2 groups in the third month, while in the fourth all the symptoms except dyspnoea displayed significant differences. The whole evaluation of the 4 months revealed a significant reduction of wheezing, nasal obstruction, sneezes, rhinorrea and night cough. Conclusions: The results demonstrate the clinical efficacy of this ultrasound device, but we cannot relate the results to the reduction of the house dust mite allergen level, as a direct measurement hasn't been conducted. The most relevant benefits were on rhinorrea, nasal obstruction, sneezes, night cough and wheezing, with a smaller effect on the reduction of other symptoms such as itchiness, exercise-induced cough and dyspnoea.
|Translated title of the contribution||Clinical efficacy of a device of ultrasonic revulsion in the therapy of children with persistent asthma due to allergy to dust mites|
|Number of pages||4|
|Journal||Italian Journal of Allergy and Clinical Immunology|
|Publication status||Published - Mar 2005|
ASJC Scopus subject areas
- Immunology and Allergy