Clinical evaluation of a (1,3)-β-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients

Valerio Del Bono, Alessandra Mularoni, Elisa Furfaro, Emanuele Delfino, Lorenzo Rosasco, Franca Miletich, Claudio Viscoli

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

(1,3)-β-D-Glucan (BG) is a component of the Pneumocystis jiroveci cell wall. Thirty-one immunocompromised patients with pneumonia (16 with presumptive pneumocystis pneumonia [PCP] and 15 with non-PCP) were evaluated for serum BG levels. Serum from all 16 presumptive PCP patients and from 2/15 patients with non-PCP was positive for BG. Results indicate that BG is a reliable marker for diagnosing PCP.

Original languageEnglish
Pages (from-to)1524-1526
Number of pages3
JournalClinical and Vaccine Immunology
Volume16
Issue number10
DOIs
Publication statusPublished - Oct 2009

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Pneumocystis carinii
Pneumocystis Pneumonia
Immunocompromised Host
Assays
Pneumonia
Cells
Serum
Cell Wall
polyglucosan

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Immunology
  • Immunology and Allergy
  • Microbiology (medical)

Cite this

Clinical evaluation of a (1,3)-β-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients. / Del Bono, Valerio; Mularoni, Alessandra; Furfaro, Elisa; Delfino, Emanuele; Rosasco, Lorenzo; Miletich, Franca; Viscoli, Claudio.

In: Clinical and Vaccine Immunology, Vol. 16, No. 10, 10.2009, p. 1524-1526.

Research output: Contribution to journalArticle

Del Bono, Valerio ; Mularoni, Alessandra ; Furfaro, Elisa ; Delfino, Emanuele ; Rosasco, Lorenzo ; Miletich, Franca ; Viscoli, Claudio. / Clinical evaluation of a (1,3)-β-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients. In: Clinical and Vaccine Immunology. 2009 ; Vol. 16, No. 10. pp. 1524-1526.
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