Clinical evaluation of a (1,3)-β-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients

Valerio Del Bono; Alessandra Mularoni; Elisa Furfaro; Emanuele Delfino; Lorenzo Rosasco; Franca Miletich; Claudio Viscoli

doi:10.1128/CVI.00276-09

Clinical evaluation of a (1,3)-β-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients

Valerio Del Bono, Alessandra Mularoni, Elisa Furfaro, Emanuele Delfino, Lorenzo Rosasco, Franca Miletich, Claudio Viscoli

Research output: Contribution to journal › Article › peer-review

Abstract

(1,3)-β-D-Glucan (BG) is a component of the Pneumocystis jiroveci cell wall. Thirty-one immunocompromised patients with pneumonia (16 with presumptive pneumocystis pneumonia [PCP] and 15 with non-PCP) were evaluated for serum BG levels. Serum from all 16 presumptive PCP patients and from 2/15 patients with non-PCP was positive for BG. Results indicate that BG is a reliable marker for diagnosing PCP.

Original language	English
Pages (from-to)	1524-1526
Number of pages	3
Journal	Clinical and Vaccine Immunology
Volume	16
Issue number	10
DOIs	https://doi.org/10.1128/CVI.00276-09
Publication status	Published - Oct 2009

ASJC Scopus subject areas

Clinical Biochemistry
Immunology
Immunology and Allergy
Microbiology (medical)

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Clinical evaluation of a (1,3)-β-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients. / Del Bono, Valerio; Mularoni, Alessandra; Furfaro, Elisa; Delfino, Emanuele; Rosasco, Lorenzo; Miletich, Franca; Viscoli, Claudio.

In: Clinical and Vaccine Immunology, Vol. 16, No. 10, 10.2009, p. 1524-1526.

Research output: Contribution to journal › Article › peer-review

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AU - Viscoli, Claudio

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