Clinical evaluation of a (1,3)-β-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients

Valerio Del Bono, Alessandra Mularoni, Elisa Furfaro, Emanuele Delfino, Lorenzo Rosasco, Franca Miletich, Claudio Viscoli

Research output: Contribution to journalArticlepeer-review

Abstract

(1,3)-β-D-Glucan (BG) is a component of the Pneumocystis jiroveci cell wall. Thirty-one immunocompromised patients with pneumonia (16 with presumptive pneumocystis pneumonia [PCP] and 15 with non-PCP) were evaluated for serum BG levels. Serum from all 16 presumptive PCP patients and from 2/15 patients with non-PCP was positive for BG. Results indicate that BG is a reliable marker for diagnosing PCP.

Original languageEnglish
Pages (from-to)1524-1526
Number of pages3
JournalClinical and Vaccine Immunology
Volume16
Issue number10
DOIs
Publication statusPublished - Oct 2009

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Immunology
  • Immunology and Allergy
  • Microbiology (medical)

Fingerprint Dive into the research topics of 'Clinical evaluation of a (1,3)-β-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients'. Together they form a unique fingerprint.

Cite this