Clinical Evaluation of Epilepsy in the Brain-Tumor Patient

Herbert B. Newton, Marta Maschio

Research output: Chapter in Book/Report/Conference proceedingChapter


Paroxysmal events in the patient with brain tumor-related epilepsy are most often seizures, but they can sometimes be other, similar-appearing events that are not associated with abnormal electrical activity in the brain. The differential diagnosis is extensive and includes cardiogenic and noncardiogenic syncope, as well as numerous other diagnoses, such as hyperventilation, cerebrovascular disease, medication side effects, neurodegenerative disorders, migraine headaches, toxic and metabolic disturbances, psychiatric disorders, movement disorders, and many others. The work-up can be extensive but may include a cardiological evaluation, neurological evaluation, toxic and metabolic assessment, neuroimaging, EEG, and, in selected cases, extended monitoring in the inpatient setting. Active treatment of the tumor, including surgical resection, radiotherapy, and chemotherapy, can have a positive impact on brain tumor-related epilepsy and reduce seizure frequency, however.

Original languageEnglish
Title of host publicationEpilepsy and Brain Tumors
PublisherElsevier Inc.
Number of pages16
ISBN (Print)9780124171268, 9780124170438
Publication statusPublished - Mar 4 2015


  • Brain tumor-related epilepsy
  • Cardiogenic
  • Differential diagnosis
  • EEG
  • Monitoring
  • Noncardiogenic
  • Syncope

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)


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