Abstract
BDDrFVIII is a B-domain deleted recombinant factor VIII (rFVIII) product for haemophilia A. Manufacture uniquely includes purification chromatography by synthetic-affinity ligand rather than murine-based monoclonal antibody, as well as an albumin-free cell culture process. BDDrFVIII was studied in 204 patients, including 62 subjects
Original language | English |
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Pages (from-to) | 869-880 |
Number of pages | 12 |
Journal | Haemophilia |
Volume | 15 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2009 |
Keywords
- BDDrFVIII
- Factor VIII
- Haemophilia
- Pharmacokinetics
ASJC Scopus subject areas
- Hematology
- Genetics(clinical)