Clinical evaluation of octatropine methylbromide plus diazepam (Valpinax* * Valpinax, Crinos S.p.A., Villaguardia (Como), Italy) in the treatment of irritable bowel syndrome

M. Guslandi, A. Evangelists, P. A. Testoni, A. Tittobello

Research output: Contribution to journalArticlepeer-review

Abstract

In a double-blind controlled study, 40 outpatients with irritable bowel syndrome were randomly treated for 40 days either with a combination of octatropine methylbromide and diazepam (Valpinax) or with placebo. The assessment of symptomatic improvement during and after the treatment showed a highly significant difference between active drug and placebo (P <0.01). No clinical side-effects were observed.

Original languageEnglish
Pages (from-to)138-144
Number of pages7
JournalClinical Trials Journal
Volume18
Issue number2
Publication statusPublished - 1981

Keywords

  • diazepam
  • Irritable bowel syndrome
  • octatropine methylbromide

ASJC Scopus subject areas

  • Pharmacology (medical)

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