Clinical expression of coronary artery ectasia

Serafina Valente, Chiara Lazzeri, Cristina Giglioli, Francesca Sani, Salvatore Mario Romano, Massimo Margheri, Marco Comeglio, Gian Franco Gensini

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: Coronary artery ectasia (CAE) is an uncommon finding at cardiac catheterisation. Our objective was to retrospectively assess the angiographic prevalence of CAE and its clinical expression. METHODS: From January 1999 to June 2001, 3870 consecutive patients underwent coronary angiography at our catheterisation laboratory. RESULTS: The prevalence of CAE was 3.6%. Most patients were male (89.2%). Type 1 CAE was observed in 20% of patients, type 2 in 11%, type 3 in 43%, and type 4 in 26%. The right coronary artery was most commonly involved (75%). In 55 patients with acute myocardial infarction, CAE within the culprit vessel was found in 32 patients (58.1%): ectasia was associated with stenosis in 29 patients, whereas isolated CAE was observed in only three patients. In 23 patients (41.8%), CAE was detected as a collateral finding in the presence of the culprit occluded, non-ectatic vessel. Overall, in the 109 patients (78%) with acute coronary syndrome, the culprit lesion was found to be related to the ectatic vessel in 46 patients (33.1%): ectasia was associated with stenosis in 39 patients, whereas isolated CAE was observed in only seven patients. In 66.9% CAE was an incidental finding on angiography. At follow-up, three patients with CAE died (2%). CONCLUSIONS: In our investigation, the angiographic prevalence of CAE was 3.6%. CAE occurred predominantly in males and more often affected the right coronary artery. It was associated with acute coronary syndrome in one third of cases. Isolated CAE was associated with a good prognosis at follow-up.

Original languageEnglish
Pages (from-to)815-820
Number of pages6
JournalJournal of Cardiovascular Medicine
Volume8
Issue number10
DOIs
Publication statusPublished - Oct 2007

Keywords

  • Acute coronary syndromes
  • Coronary artery ectasia
  • Myocardial infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Valente, S., Lazzeri, C., Giglioli, C., Sani, F., Romano, S. M., Margheri, M., Comeglio, M., & Gensini, G. F. (2007). Clinical expression of coronary artery ectasia. Journal of Cardiovascular Medicine, 8(10), 815-820. https://doi.org/10.2459/JCM.0b013e3280115667