Clinical features and MR imaging in children with repaired myelomeningocele

R. Bono, M. Inverno, G. Botteon, M. G. Bruzzone, M. A. Vaghi, C. L. Solero, E. Perlasca, E. Fedrizzi

Research output: Contribution to journalArticlepeer-review


The aim of the study is to define the role of associated malformations in the clinical evolution of children affected by myelomeningocele. MRI investigation of the spinal cord was carried out on 25 patients between the age of 7.3 and 18.10 with MMC repaired and followed up for at least 7 years. The relation between associated malformations demonstrated by MRI and clinical trend was analysed. The results are the following: 1) presence of asymptomatic tethered cord in all cases; 2) high frequency (92%) of Chiari malformation; 3) presence of syringomyelia in 20% of patients, symptomatic in 1; 4) presence of ventricular enlargement in 72% of cases without increased intracranial pressure syndrome. For a better therapeutic approach prospective MRI studies are needed in order to follow up associated malformations.

Original languageEnglish
Pages (from-to)553-559
Number of pages7
JournalItalian Journal of Neurological Sciences
Issue number7
Publication statusPublished - Oct 1993


  • MR imaging
  • Myelomeningocele
  • spinal cord malformation

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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