Clinical Features of Headache in Patients With Diagnosis of Definite Vestibular Migraine: The VM-Phenotypes Projects

R Teggi, B Colombo, R Albera, G Asprella Libonati, C Balzanelli, A Batuecas Caletrio, AP Casani, JM Espinoza-Sanchez, P Gamba, JA Lopez-Escamez, S Lucisano, Marco Mandalà, G Neri, Daniele Nuti, R Pecci, A Russo, E Martin-Sanz, R Sanz, G Tedeschi, Paola TorelliP Vannucchi, G Comi, M Bussi

Research output: Contribution to journalArticle

Abstract

Migraine is a common neurological disorder characterized by episodic headaches with specific features, presenting familial aggregation. Migraine is associated with episodic vertigo, named Vestibular Migraine (VM) whose diagnosis mainly rely on clinical history showing a temporary association of symptoms. Some patient refers symptoms occurring in pediatric age, defined “episodic symptoms which may be associated with migraine”. The aim of this cross sectional observational study was to assess migraine-related clinical features in VM subjects. For the purpose, 279 patients were recruited in different centres in Europe; data were collected by a senior neurologist or ENT specialist through a structured questionnaire. The age of onset of migraine was 21.8±9. The duration of headaches was lower than 24 hours in 79.1% of cases. Symptoms accompanying migrainous headaches were, in order of frequency, nausea (79.9%), phonophobia (54.5%), photophobia (53.8%), vomiting (29%), lightheadedness (21.1%). Visual or other auras were reported by 25.4% of subjects. A familial aggregation was referred by 67.4%, while migraine precursors were reported by 52.3% of subjects. Patients reporting nausea and vomiting during headaches more frequently experienced the same symptoms during vertigo. Comparing our results in VM subjects with previously published papers in migraine sufferers, our patients presented a lower duration of headaches and a higher rate of familial aggregation; moreover some common characters were observed in headache and vertigo attacks for accompanying symptoms like nausea and vomiting and clustering of attacks.
Original languageEnglish
Article number395
JournalFrontiers in Neurology
Volume9
DOIs
Publication statusPublished - 2018

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Migraine Disorders
Headache
Phenotype
Vertigo
Nausea
Vomiting
Hyperacusis
Photophobia
Dizziness
Nervous System Diseases
Age of Onset
Observational Studies
Cluster Analysis
Epilepsy
Cross-Sectional Studies
Pediatrics

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Clinical Features of Headache in Patients With Diagnosis of Definite Vestibular Migraine: The VM-Phenotypes Projects. / Teggi, R; Colombo, B; Albera, R; Asprella Libonati, G; Balzanelli, C; Batuecas Caletrio, A; Casani, AP; Espinoza-Sanchez, JM; Gamba, P; Lopez-Escamez, JA; Lucisano, S; Mandalà, Marco; Neri, G; Nuti, Daniele; Pecci, R; Russo, A; Martin-Sanz, E; Sanz, R; Tedeschi, G; Torelli, Paola; Vannucchi, P; Comi, G; Bussi, M.

In: Frontiers in Neurology, Vol. 9, 395, 2018.

Research output: Contribution to journalArticle

Teggi, R, Colombo, B, Albera, R, Asprella Libonati, G, Balzanelli, C, Batuecas Caletrio, A, Casani, AP, Espinoza-Sanchez, JM, Gamba, P, Lopez-Escamez, JA, Lucisano, S, Mandalà, M, Neri, G, Nuti, D, Pecci, R, Russo, A, Martin-Sanz, E, Sanz, R, Tedeschi, G, Torelli, P, Vannucchi, P, Comi, G & Bussi, M 2018, 'Clinical Features of Headache in Patients With Diagnosis of Definite Vestibular Migraine: The VM-Phenotypes Projects', Frontiers in Neurology, vol. 9, 395. https://doi.org/10.3389/fneur.2018.00395
Teggi, R ; Colombo, B ; Albera, R ; Asprella Libonati, G ; Balzanelli, C ; Batuecas Caletrio, A ; Casani, AP ; Espinoza-Sanchez, JM ; Gamba, P ; Lopez-Escamez, JA ; Lucisano, S ; Mandalà, Marco ; Neri, G ; Nuti, Daniele ; Pecci, R ; Russo, A ; Martin-Sanz, E ; Sanz, R ; Tedeschi, G ; Torelli, Paola ; Vannucchi, P ; Comi, G ; Bussi, M. / Clinical Features of Headache in Patients With Diagnosis of Definite Vestibular Migraine: The VM-Phenotypes Projects. In: Frontiers in Neurology. 2018 ; Vol. 9.
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abstract = "Migraine is a common neurological disorder characterized by episodic headaches with specific features, presenting familial aggregation. Migraine is associated with episodic vertigo, named Vestibular Migraine (VM) whose diagnosis mainly rely on clinical history showing a temporary association of symptoms. Some patient refers symptoms occurring in pediatric age, defined “episodic symptoms which may be associated with migraine”. The aim of this cross sectional observational study was to assess migraine-related clinical features in VM subjects. For the purpose, 279 patients were recruited in different centres in Europe; data were collected by a senior neurologist or ENT specialist through a structured questionnaire. The age of onset of migraine was 21.8±9. The duration of headaches was lower than 24 hours in 79.1{\%} of cases. Symptoms accompanying migrainous headaches were, in order of frequency, nausea (79.9{\%}), phonophobia (54.5{\%}), photophobia (53.8{\%}), vomiting (29{\%}), lightheadedness (21.1{\%}). Visual or other auras were reported by 25.4{\%} of subjects. A familial aggregation was referred by 67.4{\%}, while migraine precursors were reported by 52.3{\%} of subjects. Patients reporting nausea and vomiting during headaches more frequently experienced the same symptoms during vertigo. Comparing our results in VM subjects with previously published papers in migraine sufferers, our patients presented a lower duration of headaches and a higher rate of familial aggregation; moreover some common characters were observed in headache and vertigo attacks for accompanying symptoms like nausea and vomiting and clustering of attacks.",
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AU - Colombo, B

AU - Albera, R

AU - Asprella Libonati, G

AU - Balzanelli, C

AU - Batuecas Caletrio, A

AU - Casani, AP

AU - Espinoza-Sanchez, JM

AU - Gamba, P

AU - Lopez-Escamez, JA

AU - Lucisano, S

AU - Mandalà, Marco

AU - Neri, G

AU - Nuti, Daniele

AU - Pecci, R

AU - Russo, A

AU - Martin-Sanz, E

AU - Sanz, R

AU - Tedeschi, G

AU - Torelli, Paola

AU - Vannucchi, P

AU - Comi, G

AU - Bussi, M

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N2 - Migraine is a common neurological disorder characterized by episodic headaches with specific features, presenting familial aggregation. Migraine is associated with episodic vertigo, named Vestibular Migraine (VM) whose diagnosis mainly rely on clinical history showing a temporary association of symptoms. Some patient refers symptoms occurring in pediatric age, defined “episodic symptoms which may be associated with migraine”. The aim of this cross sectional observational study was to assess migraine-related clinical features in VM subjects. For the purpose, 279 patients were recruited in different centres in Europe; data were collected by a senior neurologist or ENT specialist through a structured questionnaire. The age of onset of migraine was 21.8±9. The duration of headaches was lower than 24 hours in 79.1% of cases. Symptoms accompanying migrainous headaches were, in order of frequency, nausea (79.9%), phonophobia (54.5%), photophobia (53.8%), vomiting (29%), lightheadedness (21.1%). Visual or other auras were reported by 25.4% of subjects. A familial aggregation was referred by 67.4%, while migraine precursors were reported by 52.3% of subjects. Patients reporting nausea and vomiting during headaches more frequently experienced the same symptoms during vertigo. Comparing our results in VM subjects with previously published papers in migraine sufferers, our patients presented a lower duration of headaches and a higher rate of familial aggregation; moreover some common characters were observed in headache and vertigo attacks for accompanying symptoms like nausea and vomiting and clustering of attacks.

AB - Migraine is a common neurological disorder characterized by episodic headaches with specific features, presenting familial aggregation. Migraine is associated with episodic vertigo, named Vestibular Migraine (VM) whose diagnosis mainly rely on clinical history showing a temporary association of symptoms. Some patient refers symptoms occurring in pediatric age, defined “episodic symptoms which may be associated with migraine”. The aim of this cross sectional observational study was to assess migraine-related clinical features in VM subjects. For the purpose, 279 patients were recruited in different centres in Europe; data were collected by a senior neurologist or ENT specialist through a structured questionnaire. The age of onset of migraine was 21.8±9. The duration of headaches was lower than 24 hours in 79.1% of cases. Symptoms accompanying migrainous headaches were, in order of frequency, nausea (79.9%), phonophobia (54.5%), photophobia (53.8%), vomiting (29%), lightheadedness (21.1%). Visual or other auras were reported by 25.4% of subjects. A familial aggregation was referred by 67.4%, while migraine precursors were reported by 52.3% of subjects. Patients reporting nausea and vomiting during headaches more frequently experienced the same symptoms during vertigo. Comparing our results in VM subjects with previously published papers in migraine sufferers, our patients presented a lower duration of headaches and a higher rate of familial aggregation; moreover some common characters were observed in headache and vertigo attacks for accompanying symptoms like nausea and vomiting and clustering of attacks.

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