Clinical frailty scale and outcome after coronary artery bypass grafting

Daniel Reichart; Stefano Rosato; Wail Nammas; Francesco Onorati; Magnus Dalén; Liesa Castro; Riccardo Gherli; Giuseppe Gatti; Ilaria Franzese; Giuseppe Faggian; Marisa De Feo; Sorosh Khodabandeh; Giuseppe Santarpino; Antonino S. Rubino; Daniele Maselli; Saverio Nardella; Antonio Salsano; Francesco Nicolini; Marco Zanobini; Matteo Saccocci; Karl Bounader; Eeva Maija Kinnunen; Tuomas Tauriainen; Juhani Airaksinen; Fulvia Seccareccia; Giovanni Mariscalco; Vito G. Ruggieri; Andrea Perrotti; Fausto Biancari

doi:10.1093/ejcts/ezy222

Clinical frailty scale and outcome after coronary artery bypass grafting

Daniel Reichart, Stefano Rosato, Wail Nammas, Francesco Onorati, Magnus Dalén, Liesa Castro, Riccardo Gherli, Giuseppe Gatti, Ilaria Franzese, Giuseppe Faggian, Marisa De Feo, Sorosh Khodabandeh, Giuseppe Santarpino, Antonino S. Rubino, Daniele Maselli, Saverio Nardella, Antonio Salsano, Francesco Nicolini, Marco Zanobini, Matteo SaccocciKarl Bounader, Eeva Maija Kinnunen, Tuomas Tauriainen, Juhani Airaksinen, Fulvia Seccareccia, Giovanni Mariscalco, Vito G. Ruggieri, Andrea Perrotti, Fausto Biancari

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Abstract

OBJECTIVES: The aim of this study was to assess the impact of frailty on the outcome after coronary artery bypass grafting (CABG) and whether it may improve the predictive ability of European System for Cardiac Operative Risk Evaluation (EuroSCORE II). METHODS: The Clinical Frailty Scale (CFS) was assessed preoperatively in patients undergoing isolated CABG from the multicentre E-CABG registry, and patients were stratified into 3 classes: scores 1-2, scores 3-4 and scores 5-7. RESULTS: Of the 6156 patients enrolled, 39.2% had CFS scores 1-2, 57.6% scores 3-4, and 3.2% scores 5-7. Logistic regression adjusted for multiple covariates showed that the CFS was an independent predictor of hospital/30-day mortality [CFS scores 3-4, odds ratio (OR) 3.95, 95% confidence interval (CI) 2.19-7.14; CFS scores 5-7, OR 5.90, 95% CI 2.67-13.05] and resulted in an Integrated Improvement Index of 1.3 (P

Original language	English
Pages (from-to)	1102-1109
Number of pages	8
Journal	European Journal of Cardio-thoracic Surgery
Volume	54
Issue number	6
DOIs	https://doi.org/10.1093/ejcts/ezy222
Publication status	Published - Dec 1 2018

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Reichart, D., Rosato, S., Nammas, W., Onorati, F., Dalén, M., Castro, L., Gherli, R., Gatti, G., Franzese, I., Faggian, G., De Feo, M., Khodabandeh, S., Santarpino, G., Rubino, A. S., Maselli, D., Nardella, S., Salsano, A., Nicolini, F., Zanobini, M., ... Biancari, F. (2018). Clinical frailty scale and outcome after coronary artery bypass grafting. European Journal of Cardio-thoracic Surgery, 54(6), 1102-1109. https://doi.org/10.1093/ejcts/ezy222

Reichart, D, Rosato, S, Nammas, W, Onorati, F, Dalén, M, Castro, L, Gherli, R, Gatti, G, Franzese, I, Faggian, G, De Feo, M, Khodabandeh, S, Santarpino, G, Rubino, AS, Maselli, D, Nardella, S, Salsano, A, Nicolini, F, Zanobini, M, Saccocci, M, Bounader, K, Kinnunen, EM, Tauriainen, T, Airaksinen, J, Seccareccia, F, Mariscalco, G, Ruggieri, VG, Perrotti, A & Biancari, F 2018, 'Clinical frailty scale and outcome after coronary artery bypass grafting', European Journal of Cardio-thoracic Surgery, vol. 54, no. 6, pp. 1102-1109. https://doi.org/10.1093/ejcts/ezy222

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title = "Clinical frailty scale and outcome after coronary artery bypass grafting",

abstract = "OBJECTIVES: The aim of this study was to assess the impact of frailty on the outcome after coronary artery bypass grafting (CABG) and whether it may improve the predictive ability of European System for Cardiac Operative Risk Evaluation (EuroSCORE II). METHODS: The Clinical Frailty Scale (CFS) was assessed preoperatively in patients undergoing isolated CABG from the multicentre E-CABG registry, and patients were stratified into 3 classes: scores 1-2, scores 3-4 and scores 5-7. RESULTS: Of the 6156 patients enrolled, 39.2% had CFS scores 1-2, 57.6% scores 3-4, and 3.2% scores 5-7. Logistic regression adjusted for multiple covariates showed that the CFS was an independent predictor of hospital/30-day mortality [CFS scores 3-4, odds ratio (OR) 3.95, 95% confidence interval (CI) 2.19-7.14; CFS scores 5-7, OR 5.90, 95% CI 2.67-13.05] and resulted in an Integrated Improvement Index of 1.3 (P ",

author = "Daniel Reichart and Stefano Rosato and Wail Nammas and Francesco Onorati and Magnus Dal{\'e}n and Liesa Castro and Riccardo Gherli and Giuseppe Gatti and Ilaria Franzese and Giuseppe Faggian and {De Feo}, Marisa and Sorosh Khodabandeh and Giuseppe Santarpino and Rubino, {Antonino S.} and Daniele Maselli and Saverio Nardella and Antonio Salsano and Francesco Nicolini and Marco Zanobini and Matteo Saccocci and Karl Bounader and Kinnunen, {Eeva Maija} and Tuomas Tauriainen and Juhani Airaksinen and Fulvia Seccareccia and Giovanni Mariscalco and Ruggieri, {Vito G.} and Andrea Perrotti and Fausto Biancari",

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doi = "10.1093/ejcts/ezy222",

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T1 - Clinical frailty scale and outcome after coronary artery bypass grafting

AU - Reichart, Daniel

AU - Rosato, Stefano

AU - Nammas, Wail

AU - Onorati, Francesco

AU - Dalén, Magnus

AU - Castro, Liesa

AU - Gherli, Riccardo

AU - Gatti, Giuseppe

AU - Franzese, Ilaria

AU - Faggian, Giuseppe

AU - De Feo, Marisa

AU - Khodabandeh, Sorosh

AU - Santarpino, Giuseppe

AU - Rubino, Antonino S.

AU - Maselli, Daniele

AU - Nardella, Saverio

AU - Salsano, Antonio

AU - Nicolini, Francesco

AU - Zanobini, Marco

AU - Saccocci, Matteo

AU - Bounader, Karl

AU - Kinnunen, Eeva Maija

AU - Tauriainen, Tuomas

AU - Airaksinen, Juhani

AU - Seccareccia, Fulvia

AU - Mariscalco, Giovanni

AU - Ruggieri, Vito G.

AU - Perrotti, Andrea

AU - Biancari, Fausto

PY - 2018/12/1

Y1 - 2018/12/1

N2 - OBJECTIVES: The aim of this study was to assess the impact of frailty on the outcome after coronary artery bypass grafting (CABG) and whether it may improve the predictive ability of European System for Cardiac Operative Risk Evaluation (EuroSCORE II). METHODS: The Clinical Frailty Scale (CFS) was assessed preoperatively in patients undergoing isolated CABG from the multicentre E-CABG registry, and patients were stratified into 3 classes: scores 1-2, scores 3-4 and scores 5-7. RESULTS: Of the 6156 patients enrolled, 39.2% had CFS scores 1-2, 57.6% scores 3-4, and 3.2% scores 5-7. Logistic regression adjusted for multiple covariates showed that the CFS was an independent predictor of hospital/30-day mortality [CFS scores 3-4, odds ratio (OR) 3.95, 95% confidence interval (CI) 2.19-7.14; CFS scores 5-7, OR 5.90, 95% CI 2.67-13.05] and resulted in an Integrated Improvement Index of 1.3 (P

AB - OBJECTIVES: The aim of this study was to assess the impact of frailty on the outcome after coronary artery bypass grafting (CABG) and whether it may improve the predictive ability of European System for Cardiac Operative Risk Evaluation (EuroSCORE II). METHODS: The Clinical Frailty Scale (CFS) was assessed preoperatively in patients undergoing isolated CABG from the multicentre E-CABG registry, and patients were stratified into 3 classes: scores 1-2, scores 3-4 and scores 5-7. RESULTS: Of the 6156 patients enrolled, 39.2% had CFS scores 1-2, 57.6% scores 3-4, and 3.2% scores 5-7. Logistic regression adjusted for multiple covariates showed that the CFS was an independent predictor of hospital/30-day mortality [CFS scores 3-4, odds ratio (OR) 3.95, 95% confidence interval (CI) 2.19-7.14; CFS scores 5-7, OR 5.90, 95% CI 2.67-13.05] and resulted in an Integrated Improvement Index of 1.3 (P

U2 - 10.1093/ejcts/ezy222

DO - 10.1093/ejcts/ezy222

M3 - Article

VL - 54

SP - 1102

EP - 1109

JO - European Journal of Cardio-thoracic Surgery

JF - European Journal of Cardio-thoracic Surgery

SN - 1010-7940

IS - 6

ER -

Clinical frailty scale and outcome after coronary artery bypass grafting

Abstract

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