Clinical implications of differences between angiotensin II antagonists

Peter S. Sever, Giuseppe Mancia

Research output: Contribution to journalArticlepeer-review


Adequate control of high blood pressure has long been difficult, and several issues concerning antihypertensive medications confront the practicing physician. First, treatment with one medication has rarely proven to achieve the blood pressure lowering effect desired for individual patients. Furthermore, differences between medications in the same drug class can be significant as can those between medications belonging to different drug classes. Efficacy, according to these presenters, will be the ultimate gauge by which antihypertensive treatments are judged. However, efficacy includes a variety of components, and more information is rapidly becoming available on all the effects of these treatments. The ability of a particular drug to maintain a steady level of blood pressure control throughout the dosing period is one of the most important of these factors and appears to help reverse some important cardiovascular and end-organ damage associated with the disease.

Original languageEnglish
JournalAmerican Journal of Managed Care
Issue number7 SUPPL.
Publication statusPublished - Jul 1998

ASJC Scopus subject areas

  • Medicine(all)
  • Nursing(all)
  • Health(social science)
  • Health Professions(all)


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