Clinical management of a case of recurrent apocrine gland carcinoma of the scalp

Efficacy of a chemotherapy schedule with methotrexate and bleomycin

A. Morabito, P. Bevilacqua, S. Vitale, M. Fanelli, D. Gattuso, G. Gasparini

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Apocrine carcinoma of the skin is a rare tumor. Wide surgical excision with complete removal of the neoplasm is the standard therapy and this appears to offer the best chance of cure. Radiotherapy may be used in case of local relapse or regional lymph node involvement. Systemic chemotherapy has not proved to be effective in the treatment of this tumor. We report on a 46-year-old woman with a recurrent apocrine carcinoma of the scalp that had previously been treated with surgery, radiotherapy and chemotherapy (Al-Saraff schedule). The patient was responsive to a second-line systemic chemotherapy regimen consisting of a weekly combination of methotrexate and bleomycin, and achieved long-term progression-free survival.

Original languageEnglish
Pages (from-to)472-474
Number of pages3
JournalTumori
Volume86
Issue number6
Publication statusPublished - 2000

Fingerprint

Apocrine Glands
Bleomycin
Case Management
Scalp
Methotrexate
Appointments and Schedules
Carcinoma
Drug Therapy
Radiotherapy
Neoplasms
Disease-Free Survival
Lymph Nodes
Recurrence
Skin
Therapeutics

Keywords

  • Apocrine carcinoma
  • Chemotherapy
  • Outcome

ASJC Scopus subject areas

  • Cancer Research

Cite this

Clinical management of a case of recurrent apocrine gland carcinoma of the scalp : Efficacy of a chemotherapy schedule with methotrexate and bleomycin. / Morabito, A.; Bevilacqua, P.; Vitale, S.; Fanelli, M.; Gattuso, D.; Gasparini, G.

In: Tumori, Vol. 86, No. 6, 2000, p. 472-474.

Research output: Contribution to journalArticle

Morabito, A. ; Bevilacqua, P. ; Vitale, S. ; Fanelli, M. ; Gattuso, D. ; Gasparini, G. / Clinical management of a case of recurrent apocrine gland carcinoma of the scalp : Efficacy of a chemotherapy schedule with methotrexate and bleomycin. In: Tumori. 2000 ; Vol. 86, No. 6. pp. 472-474.
@article{fa932e111127483b872607ac9d7f078f,
title = "Clinical management of a case of recurrent apocrine gland carcinoma of the scalp: Efficacy of a chemotherapy schedule with methotrexate and bleomycin",
abstract = "Apocrine carcinoma of the skin is a rare tumor. Wide surgical excision with complete removal of the neoplasm is the standard therapy and this appears to offer the best chance of cure. Radiotherapy may be used in case of local relapse or regional lymph node involvement. Systemic chemotherapy has not proved to be effective in the treatment of this tumor. We report on a 46-year-old woman with a recurrent apocrine carcinoma of the scalp that had previously been treated with surgery, radiotherapy and chemotherapy (Al-Saraff schedule). The patient was responsive to a second-line systemic chemotherapy regimen consisting of a weekly combination of methotrexate and bleomycin, and achieved long-term progression-free survival.",
keywords = "Apocrine carcinoma, Chemotherapy, Outcome",
author = "A. Morabito and P. Bevilacqua and S. Vitale and M. Fanelli and D. Gattuso and G. Gasparini",
year = "2000",
language = "English",
volume = "86",
pages = "472--474",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "6",

}

TY - JOUR

T1 - Clinical management of a case of recurrent apocrine gland carcinoma of the scalp

T2 - Efficacy of a chemotherapy schedule with methotrexate and bleomycin

AU - Morabito, A.

AU - Bevilacqua, P.

AU - Vitale, S.

AU - Fanelli, M.

AU - Gattuso, D.

AU - Gasparini, G.

PY - 2000

Y1 - 2000

N2 - Apocrine carcinoma of the skin is a rare tumor. Wide surgical excision with complete removal of the neoplasm is the standard therapy and this appears to offer the best chance of cure. Radiotherapy may be used in case of local relapse or regional lymph node involvement. Systemic chemotherapy has not proved to be effective in the treatment of this tumor. We report on a 46-year-old woman with a recurrent apocrine carcinoma of the scalp that had previously been treated with surgery, radiotherapy and chemotherapy (Al-Saraff schedule). The patient was responsive to a second-line systemic chemotherapy regimen consisting of a weekly combination of methotrexate and bleomycin, and achieved long-term progression-free survival.

AB - Apocrine carcinoma of the skin is a rare tumor. Wide surgical excision with complete removal of the neoplasm is the standard therapy and this appears to offer the best chance of cure. Radiotherapy may be used in case of local relapse or regional lymph node involvement. Systemic chemotherapy has not proved to be effective in the treatment of this tumor. We report on a 46-year-old woman with a recurrent apocrine carcinoma of the scalp that had previously been treated with surgery, radiotherapy and chemotherapy (Al-Saraff schedule). The patient was responsive to a second-line systemic chemotherapy regimen consisting of a weekly combination of methotrexate and bleomycin, and achieved long-term progression-free survival.

KW - Apocrine carcinoma

KW - Chemotherapy

KW - Outcome

UR - http://www.scopus.com/inward/record.url?scp=0034491914&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034491914&partnerID=8YFLogxK

M3 - Article

VL - 86

SP - 472

EP - 474

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 6

ER -