Clinical management of patients with a history of urticaria/angioedema induced by multiple NSAIDs: An expert panel review

Riccardo Asero, Sevim Bavbek, Miguel Blanca, Natalia Blanca-Lopez, Gabriele Cortellini, Ewa Nizankowska-Mogilnicka, Donato Quaratino, Antonino Romano, Mario Sanchez-Borges, Maria Josè Torres-Jaen

Research output: Contribution to journalArticlepeer-review

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most frequent causes of drug-induced urticaria/angioedema worldwide. Recent review articles have classified patients experiencing NSAID-induced urticaria/angioedema into different categories, including single reactors, multiple reactors, and multiple reactors with underlying chronic urticaria. Each of these categories requires a different clinical approach. The present article, written by a panel of experts, reports the main recommendations for the practical clinical management of patients with a history of urticaria/angioedema induced by multiple NSAID based on current knowledge.

Original languageEnglish
Pages (from-to)126-133
Number of pages8
JournalInternational Archives of Allergy and Immunology
Volume160
Issue number2
DOIs
Publication statusPublished - Jan 2013

Keywords

  • COX-1
  • COX-2
  • Cross-reactivity
  • Nonsteroidal anti-inflammatory drug hypersensitivity
  • NSAID
  • Oral challenge tests
  • Urticaria

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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