TY - JOUR
T1 - Clinical manifestations of Behçet's disease in 137 Italian patients
T2 - Results of a multicenter study
AU - Pipitone, Nicolò
AU - Boiardi, Luigi
AU - Olivieri, Ignazio
AU - Cantini, Fabrizio
AU - Salvi, Fabrizio
AU - Malatesta, Renato
AU - La Corte, Renato
AU - Triolo, Giovanni
AU - Ferrante, Angelo
AU - Filippini, Davide
AU - Paolazzi, Giuseppe
AU - Sarzi-Puttini, Piercarlo
AU - Restuccia, Giovanna
AU - Salvarani, Carlo
PY - 2004
Y1 - 2004
N2 - Objective. To determine the type and frequency of clinical features of Behçet's disease in a population of Italian patients. Methods. We retrospectively studied 137 Italian patients (76 males and 61 females, age at onset 29.6 ± 12.2 [mean ± SD] years) seen consecutively in nine different referral centers. The duration of follow-up at study entry was 10.9 ± 8.2 years. Virtually all patients fulfilled the classification criteria developed by the International Study Group for Behçet's disease. The clinical manifestations of the patients were recorded by the attending physicians using specifically designed forms. Results. The most frequent manifestations at disease onset were oral (78.3%) and genital aphthae (29.2%) followed by inflammatory ocular involvement (20%) and arthritis (14.2%). The commonest (>50% of cases) manifestations observed throughout the disease course were oral aphthae (99.3%), genital aphthae (62.8%), various cutaneous lesions including erythema nodosum (81.8%), and inflammatory ocular disease (60.6%). Panuveitis and posterior uveitis/retinitis occurred more frequently in males compared with females (28.9% versus 11.5% and 57.9% versus 36.1%, respectively; p
AB - Objective. To determine the type and frequency of clinical features of Behçet's disease in a population of Italian patients. Methods. We retrospectively studied 137 Italian patients (76 males and 61 females, age at onset 29.6 ± 12.2 [mean ± SD] years) seen consecutively in nine different referral centers. The duration of follow-up at study entry was 10.9 ± 8.2 years. Virtually all patients fulfilled the classification criteria developed by the International Study Group for Behçet's disease. The clinical manifestations of the patients were recorded by the attending physicians using specifically designed forms. Results. The most frequent manifestations at disease onset were oral (78.3%) and genital aphthae (29.2%) followed by inflammatory ocular involvement (20%) and arthritis (14.2%). The commonest (>50% of cases) manifestations observed throughout the disease course were oral aphthae (99.3%), genital aphthae (62.8%), various cutaneous lesions including erythema nodosum (81.8%), and inflammatory ocular disease (60.6%). Panuveitis and posterior uveitis/retinitis occurred more frequently in males compared with females (28.9% versus 11.5% and 57.9% versus 36.1%, respectively; p
KW - Behçet syndrome
KW - Italy
KW - Signs and symptoms
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M3 - Article
C2 - 15675135
AN - SCOPUS:15044350747
VL - 22
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
SN - 0392-856X
IS - 6 SUPPL.
ER -