Clinical Outcomes After Implantation of Overlapping Bioresorbable Scaffolds vs New Generation Everolimus Eluting Stents

Vasileios F. Panoulas, Hiroyoshi Kawamoto, Katsumasa Sato, Tadashi Miyazaki, Toru Naganuma, Alessandro Sticchi, Azeem Latib, Antonio Colombo

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction and objectives: There is limited evidence on procedural and clinical outcomes in patients treated with overlapping bioresorbable scaffolds vs overlapping everolimus-eluting stents. We evaluated the outcomes of propensity-matched patients treated with overlapping scaffolds vs everolimus-eluting stents. Methods: After propensity matching, 70 consecutive stable angina patients treated with overlapping bioresorbable scaffolds and 70 patients treated with overlapping new generation everolimus stents were included in this study. The primary outcome was the 1-year rate of major adverse cardiovascular events, defined as the composite of all-cause mortality, nonprocedural myocardial infarction, and target-vessel revascularization. Results: Patients in the 2 groups had similar age (scaffold vs stent: 64.5 ± 10.3 vs 66 ± 9.7 years; P =.381), sex, diabetes, previous cardiovascular history, and SYNTAX score (scaffold vs stent: 18.6 ± 9.2 vs 19.4 ± 10.4; P =.635). Postprocedural acute gain was significantly lower in patients treated with scaffolds (1.82±0.66 vs 2.03±0.68mm; P =.033). At 1-year follow up, the estimated major adverse cardiovascular event rate was not significantly different between the 2 groups (scaffold vs stent: 14.5% vs 14.6%; P log-rank =.661). Similarly, no significant differences were seen in 1-year rates of target vessel (scaffold vs stent: 14.5% vs 10%; P log-rank =.816) or target lesion revascularization (scaffold vs stent: 9.7% vs 8.3%; P log-rank =.815). Conclusions: Treating long lesions with overlapping scaffolds is feasible with acceptable 1-year outcomes. Full English text available from: www.revespcardiol.org/en

Original languageSpanish
JournalRevista Espanola de Cardiologia
DOIs
Publication statusAccepted/In press - Dec 7 2015

Keywords

  • Bioresorbable scaffold
  • Drug eluting stent
  • Everolimus-eluting stent
  • Overlap
  • Strut

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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