Clinical outcomes of a real-world cohort following bioresorbable vascular scaffold implantation utilising an optimised implantation strategy

Akihito Tanaka, A Latib, H Kawamoto, RJ Jabbour, K Sato, T Miyazaki, T Naganuma, A Mangieri, M Pagnesi, Claudio Montalto, A Chieffo, M Carlino, M Montorfano, A Colombo

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Abstract

Aims: It has become apparent that, in comparison to metallic stents, bioresorbable vascular scaffolds (BVS) require specific implantation techniques. The aim of this study was to investigate outcomes following BVS implantation using a dedicated strategy for optimal deployment. Methods and results: Four hundred consecutive lesions (264 patients) treated with the Absorb BVS were analysed. All procedures were performed based on the following principles: 1) aggressive lesion preparation; 2) high-pressure post-dilation; and 3) a low threshold for intravascular imaging. The majority of target lesions (74.8%) were type B2 or C lesions. Predilation (97.3%) and post-dilation (99.8%) were performed in almost all cases. The mean post-dilation pressure was 21±5 atm, and the total scaffold length per patient was 53.2±32.5 mm. Intravascular imaging was performed in the majority of cases (85.8%) and, when utilised after post-dilatation, a further intervention was required in 24.5% of lesions. The cumulative target lesion failure rates were 7.9% at one year and 11.6% at two years. Definite/probable scaffold thrombosis occurred in three patients (1.2% at one and two years). Conclusions: Clinical outcomes following implantation of current-generation BVS, in a real-world population with a high prevalence of complex lesions, were acceptable when utilising our optimised implantation strategy. © Europa Digital & Publishing 2017. All rights reserved.
Original languageEnglish
Pages (from-to)1730-1737
Number of pages8
JournalEuroIntervention
Volume12
Issue number14
DOIs
Publication statusPublished - 2017

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    Tanaka, A., Latib, A., Kawamoto, H., Jabbour, RJ., Sato, K., Miyazaki, T., Naganuma, T., Mangieri, A., Pagnesi, M., Montalto, C., Chieffo, A., Carlino, M., Montorfano, M., & Colombo, A. (2017). Clinical outcomes of a real-world cohort following bioresorbable vascular scaffold implantation utilising an optimised implantation strategy. EuroIntervention, 12(14), 1730-1737. https://doi.org/10.4244/EIJ-D-16-00247