A group of 47 patients (multiple sclerosis (M.S.) diagnosed according to Schumacher's criteria) with age at onset over 40 yr, was studied by statistical analysis and compared with a control group (100 M.S. patients with onset between ages 18 and 38). The following features appear peculiar in this group: the most frequent initial symptoms are motor disturbances: the onset is generally monosymptomatic; the course is generally progressive and more severe than that of controls, as seen by Kurtzke's Disability Scale, relapse rate, interval between first and second attack; and the course is more severe when the onset is progressive and characterized by motor disturbances.
|Number of pages||7|
|Journal||Acta Neurologica Scandinavica|
|Publication status||Published - 1978|
ASJC Scopus subject areas
- Clinical Neurology