Clinical picture of multiple sclerosis with late onset

C. L. Cazzullo, A. Ghezzi, S. Marforio, D. Caputo

Research output: Contribution to journalArticlepeer-review


A group of 47 patients (multiple sclerosis (M.S.) diagnosed according to Schumacher's criteria) with age at onset over 40 yr, was studied by statistical analysis and compared with a control group (100 M.S. patients with onset between ages 18 and 38). The following features appear peculiar in this group: the most frequent initial symptoms are motor disturbances: the onset is generally monosymptomatic; the course is generally progressive and more severe than that of controls, as seen by Kurtzke's Disability Scale, relapse rate, interval between first and second attack; and the course is more severe when the onset is progressive and characterized by motor disturbances.

Original languageEnglish
Pages (from-to)190-196
Number of pages7
JournalActa Neurologica Scandinavica
Issue number3
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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