TY - JOUR
T1 - Clinical Predictive Circulating Peptides in Rectal Cancer Patients Treated with Neoadjuvant Chemoradiotherapy
AU - Crotti, Sara
AU - Enzo, Maria Vittoria
AU - Bedin, Chiara
AU - Pucciarelli, Salvatore
AU - Maretto, Isacco
AU - Del Bianco, Paola
AU - Traldi, Pietro
AU - Tasciotti, Ennio
AU - Ferrari, Mauro
AU - Rizzolio, Flavio
AU - Toffoli, Giuseppe
AU - Giordano, Antonio
AU - Nitti, Donato
AU - Agostini, Marco
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Preoperative chemoradiotherapy is worldwide accepted as a standard treatment for locally advanced rectal cancer. Current standard of treatment includes administration of ionizing radiation for 45-50.4Gy in 25-28 fractions associated with 5-fluorouracil administration during radiation therapy. Unfortunately, 40% of patients have a poor or absent response and novel predictive biomarkers are demanding. For the first time, we apply a novel peptidomic methodology and analysis in rectal cancer patients treated with preoperative chemoradiotherapy. Circulating peptides (Molecular Weight
AB - Preoperative chemoradiotherapy is worldwide accepted as a standard treatment for locally advanced rectal cancer. Current standard of treatment includes administration of ionizing radiation for 45-50.4Gy in 25-28 fractions associated with 5-fluorouracil administration during radiation therapy. Unfortunately, 40% of patients have a poor or absent response and novel predictive biomarkers are demanding. For the first time, we apply a novel peptidomic methodology and analysis in rectal cancer patients treated with preoperative chemoradiotherapy. Circulating peptides (Molecular Weight
UR - http://www.scopus.com/inward/record.url?scp=84928394287&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84928394287&partnerID=8YFLogxK
U2 - 10.1002/jcp.24894
DO - 10.1002/jcp.24894
M3 - Article
C2 - 25522009
AN - SCOPUS:84928394287
VL - 230
SP - 1822
EP - 1828
JO - Journal of cellular and comparative physiology
JF - Journal of cellular and comparative physiology
SN - 0021-9541
IS - 8
ER -