Clinical profiles and outcomes of acute type B aortic dissection in the current era: Lessons from the International Registry of Aortic Dissection (IRAD)

Toru Suzuki, Rajendra H. Mehta, Hüseyin Ince, Ryozo Nagai, Yasunari Sakomura, Frank Weber, Tetsuya Sumiyoshi, Eduardo Bossone, Santi Trimarchi, Jeanna V. Cooper, Dean E. Smith, Eric M. Isselbacher, Kim A. Eagle, Christoph A. Nienaber

Research output: Contribution to journalArticle

399 Citations (Scopus)

Abstract

Background - Clinical profiles and outcomes of patients with acute type B aortic dissection have not been evaluated in the current era. Methods and Results - Accordingly, we analyzed 384 patients (65±13 years, males 71%) with acute type B aortic dissection enrolled in the International Registry of Acute Aortic Dissection (IRAD). A majority of patients had hypertension and presented with acute chest/back pain. Only one-half showed abnormal findings on chest radiograph, and almost all patients had computerized tomography (CT), transesophageal echocardiography, magnetic resonance imaging (MRI), and/or aortogram to confirm the diagnosis. In-hospital mortality was 13% with most deaths occurring within the first week. Factors associated with increased in-hospital mortality on univariate analysis were hypotension/ shock, widened mediastinum, periaortic hematoma, excessively dilated aorta (≥6 cm), in-hospital complications of coma/altered consciousness, mesenteric/limb ischemia, acute renal failure, and surgical management (all P

Original languageEnglish
JournalCirculation
Volume108
Issue number10 SUPPL.
Publication statusPublished - Sep 9 2003

Fingerprint

Registries
Dissection
Hospital Mortality
Transesophageal Echocardiography
Acute Pain
Mediastinum
Back Pain
Coma
Consciousness
Chest Pain
Acute Kidney Injury
Hematoma
Hypotension
Aorta
Shock
Thorax
Extremities
Tomography
Magnetic Resonance Imaging
Hypertension

Keywords

  • Aorta
  • Aortic dissection
  • Outcomes
  • Peripheral vascular disease
  • Stents

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Suzuki, T., Mehta, R. H., Ince, H., Nagai, R., Sakomura, Y., Weber, F., ... Nienaber, C. A. (2003). Clinical profiles and outcomes of acute type B aortic dissection in the current era: Lessons from the International Registry of Aortic Dissection (IRAD). Circulation, 108(10 SUPPL.).

Clinical profiles and outcomes of acute type B aortic dissection in the current era : Lessons from the International Registry of Aortic Dissection (IRAD). / Suzuki, Toru; Mehta, Rajendra H.; Ince, Hüseyin; Nagai, Ryozo; Sakomura, Yasunari; Weber, Frank; Sumiyoshi, Tetsuya; Bossone, Eduardo; Trimarchi, Santi; Cooper, Jeanna V.; Smith, Dean E.; Isselbacher, Eric M.; Eagle, Kim A.; Nienaber, Christoph A.

In: Circulation, Vol. 108, No. 10 SUPPL., 09.09.2003.

Research output: Contribution to journalArticle

Suzuki, T, Mehta, RH, Ince, H, Nagai, R, Sakomura, Y, Weber, F, Sumiyoshi, T, Bossone, E, Trimarchi, S, Cooper, JV, Smith, DE, Isselbacher, EM, Eagle, KA & Nienaber, CA 2003, 'Clinical profiles and outcomes of acute type B aortic dissection in the current era: Lessons from the International Registry of Aortic Dissection (IRAD)', Circulation, vol. 108, no. 10 SUPPL..
Suzuki, Toru ; Mehta, Rajendra H. ; Ince, Hüseyin ; Nagai, Ryozo ; Sakomura, Yasunari ; Weber, Frank ; Sumiyoshi, Tetsuya ; Bossone, Eduardo ; Trimarchi, Santi ; Cooper, Jeanna V. ; Smith, Dean E. ; Isselbacher, Eric M. ; Eagle, Kim A. ; Nienaber, Christoph A. / Clinical profiles and outcomes of acute type B aortic dissection in the current era : Lessons from the International Registry of Aortic Dissection (IRAD). In: Circulation. 2003 ; Vol. 108, No. 10 SUPPL.
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