Clinical Reasoning: A 75-year-old man with parkinsonism, mood depression, and weight loss

Emanuele Frattini, Edoardo Monfrini, Giacomo Bitetto, Barbara Ferrari, Sara Arcudi, Nereo Bresolin, Maria Cristina Saetti, Alessio Di Fonzo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 75-year-old man presented to the emergency department with a 1-year history of 66-pound weight loss and alternating bowel habits. He was admitted to the hospital, where he underwent several examinations to investigate the presence of a malignancy. A colonoscopy, a gastroscopy, an ultrasound of the abdomen, and a contrast-enhanced CT scan of thorax and abdomen did not detect any neoplasia. The only findings consisted of a prostatic hypertrophy and a basal pleural-parenchymal hyperdensity in the left lung, which was described as the result of an infective process. Neoplastic markers CA19.9, carcinoembryonic antigen, neuron-specific enolase, and α-fetoprotein were also negative. Wide-spectrum blood tests were unremarkable, except for hypogammaglobulinemia and elevated β2 microglobulin.

Original languageEnglish
Pages (from-to)572-575
Number of pages4
JournalNeurology
Volume90
Issue number12
DOIs
Publication statusPublished - Mar 20 2018

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Parkinsonian Disorders
Abdomen
Weight Loss
Depression
Fetal Proteins
Agammaglobulinemia
Gastroscopy
Phosphopyruvate Hydratase
Carcinoembryonic Antigen
Prostatic Hyperplasia
Hematologic Tests
Colonoscopy
Habits
Hospital Emergency Service
Neoplasms
Thorax
Lung

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Clinical Reasoning : A 75-year-old man with parkinsonism, mood depression, and weight loss. / Frattini, Emanuele; Monfrini, Edoardo; Bitetto, Giacomo; Ferrari, Barbara; Arcudi, Sara; Bresolin, Nereo; Saetti, Maria Cristina; Di Fonzo, Alessio.

In: Neurology, Vol. 90, No. 12, 20.03.2018, p. 572-575.

Research output: Contribution to journalArticle

Frattini, Emanuele ; Monfrini, Edoardo ; Bitetto, Giacomo ; Ferrari, Barbara ; Arcudi, Sara ; Bresolin, Nereo ; Saetti, Maria Cristina ; Di Fonzo, Alessio. / Clinical Reasoning : A 75-year-old man with parkinsonism, mood depression, and weight loss. In: Neurology. 2018 ; Vol. 90, No. 12. pp. 572-575.
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