Clinical Reasoning: A case of COVID-19-associated pharyngeal-cervical-brachial variant of Guillain-Barré syndrome

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Abstract

In March 2020, a 49-year-old man was admitted through our emergency department due to a 1-week history of fever (39-40°C) and cough. His medical history included arterial hypertension and a testicular seminoma in 2011 treated with surgery and platinum-based chemotherapy. Laboratory tests revealed increased C-reactive protein, mild lymphopenia, and thrombocytopenia. Chest CT showed multifocal ground-glass opacities and nasopharyngeal swab was positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to a diagnosis of coronavirus disease 2019 (COVID-19). The patient was hospitalized and treatment with hydroxychloroquine, lopinavir/ritonavir, and ceftriaxone was started.

Original languageEnglish
Pages (from-to)978-983
Number of pages6
JournalNeurology
Volume95
Issue number21
DOIs
Publication statusPublished - Nov 24 2020

Keywords

  • Antiviral Agents/therapeutic use
  • Bradycardia/physiopathology
  • COVID-19/complications
  • Deglutition Disorders/physiopathology
  • Diagnosis, Differential
  • Dysphonia/physiopathology
  • Facial Nerve Diseases/physiopathology
  • Gastroparesis/physiopathology
  • Guillain-Barre Syndrome/diagnosis
  • Humans
  • Hypertension/physiopathology
  • Hypoglossal Nerve Diseases/physiopathology
  • Male
  • Middle Aged
  • Muscle Weakness/physiopathology
  • Neck Muscles/physiopathology
  • Polyneuropathies/diagnosis
  • Respiration, Artificial
  • Respiratory Insufficiency/therapy
  • Tachycardia/physiopathology
  • Upper Extremity

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