Clinical relevance of sampling rate in the characterization and analysis of 24-hour gastric acidity: A report on 413 cases

G. S. Mela, V. Savarino, M. Moreiti, G. Bonifacino, A. Sumberaz, P. Zentilin

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Four hundred and thirteen continuous, high-frequency-sampled gastric pH-metries were subdivided into six groups (normal subjects and patients with duodenal ulcer, gastric ulcer, chronic gastritis, prior cholecystectomy, or antisecretory treatment). The frequency distribution of those pH fluctuations that were greater than the quantitation error of instruments did not differ significantly (p > 0.30) between groups, Five per cent of these real pH fluctuations lasted less than 3 min. As the sampling rate increased from 1 to 60 min, the percentage of subjects whose 24-h median of pHs differed by no more than ±10% from that calculated on the raw high-frequency-acquired data progressively decreased (99.8%42% This error propagation was more marked in the case of [H+] integrals (99%10% A sampling rate equal to or faster than 1 min is necessary to provide a proper representation of the circadian pH pattern and to calculate accurate acidity indexes, regardless of the physiologic or pharmacologic nature of the profile.

Original languageEnglish
Pages (from-to)683-687
Number of pages5
JournalScandinavian Journal of Gastroenterology
Volume24
Issue number6
DOIs
Publication statusPublished - 1989

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Stomach
Cholecystectomy
Gastritis
Stomach Ulcer
Duodenal Ulcer
Therapeutics

Keywords

  • Continuous pH monitoring
  • Error propagation
  • Gastric acidity
  • Instrument error
  • Sampling rate

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Clinical relevance of sampling rate in the characterization and analysis of 24-hour gastric acidity : A report on 413 cases. / Mela, G. S.; Savarino, V.; Moreiti, M.; Bonifacino, G.; Sumberaz, A.; Zentilin, P.

In: Scandinavian Journal of Gastroenterology, Vol. 24, No. 6, 1989, p. 683-687.

Research output: Contribution to journalArticle

Mela, G. S. ; Savarino, V. ; Moreiti, M. ; Bonifacino, G. ; Sumberaz, A. ; Zentilin, P. / Clinical relevance of sampling rate in the characterization and analysis of 24-hour gastric acidity : A report on 413 cases. In: Scandinavian Journal of Gastroenterology. 1989 ; Vol. 24, No. 6. pp. 683-687.
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