Abstract
Background: Spitz nevus has clinically been described as a dome-shaped usually nonpigmented papular or nodular lesion variable in color from pink to red. Objectives: To give an exhaustive description of the clinical features of the Spitz nevus from a large series of 247 patients. Methods: A retrospective analysis of the clinical features of 247 Spitz nevi excised from 1974 to 1993 has been performed. We evaluated the following features: age, sex, anatomical location, clinical and histopathologic features; descriptive statistics were calculated and relationships among the above variables were assessed. Results: Most lesions were pigmented (71.7%), located on the lower extremities (43.3%), more frequent in the first decade (55.8%) and in females (57.9%). The nonpigmented type was more frequent in the head or neck region, whereas the pigmented types were more frequent on the lower extremities. Besides, these types showed different histopathologic features: the spindle cells usually predominated in the flat pigmented type, whereas dome-shaped types were usually composed of both spindle and epithelioid cells. Conclusions: In our patients, the pigmented Spitz nevi were more common than the nonpigmented ones; furthermore pigmented and nonpigmented Spitz nevi showed different anatomical locations and different histopathologic features.
| Original language | English |
|---|---|
| Pages (from-to) | 20-25 |
| Number of pages | 6 |
| Journal | Dermatology |
| Volume | 194 |
| Issue number | 1 |
| Publication status | Published - 1997 |
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Keywords
- Epithelioid cell nevus
- Spindle cell nevus
- Spitz nevus
ASJC Scopus subject areas
- Dermatology
Cite this
Clinical review of 247 case records of spitz nevus (epithelioid cell and/or spindle cell nevus). / Dal Pozzo, V.; Benelli, C.; Restano, L.; Gianotti, R.; Cesana, B. M.
In: Dermatology, Vol. 194, No. 1, 1997, p. 20-25.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical review of 247 case records of spitz nevus (epithelioid cell and/or spindle cell nevus)
AU - Dal Pozzo, V.
AU - Benelli, C.
AU - Restano, L.
AU - Gianotti, R.
AU - Cesana, B. M.
PY - 1997
Y1 - 1997
N2 - Background: Spitz nevus has clinically been described as a dome-shaped usually nonpigmented papular or nodular lesion variable in color from pink to red. Objectives: To give an exhaustive description of the clinical features of the Spitz nevus from a large series of 247 patients. Methods: A retrospective analysis of the clinical features of 247 Spitz nevi excised from 1974 to 1993 has been performed. We evaluated the following features: age, sex, anatomical location, clinical and histopathologic features; descriptive statistics were calculated and relationships among the above variables were assessed. Results: Most lesions were pigmented (71.7%), located on the lower extremities (43.3%), more frequent in the first decade (55.8%) and in females (57.9%). The nonpigmented type was more frequent in the head or neck region, whereas the pigmented types were more frequent on the lower extremities. Besides, these types showed different histopathologic features: the spindle cells usually predominated in the flat pigmented type, whereas dome-shaped types were usually composed of both spindle and epithelioid cells. Conclusions: In our patients, the pigmented Spitz nevi were more common than the nonpigmented ones; furthermore pigmented and nonpigmented Spitz nevi showed different anatomical locations and different histopathologic features.
AB - Background: Spitz nevus has clinically been described as a dome-shaped usually nonpigmented papular or nodular lesion variable in color from pink to red. Objectives: To give an exhaustive description of the clinical features of the Spitz nevus from a large series of 247 patients. Methods: A retrospective analysis of the clinical features of 247 Spitz nevi excised from 1974 to 1993 has been performed. We evaluated the following features: age, sex, anatomical location, clinical and histopathologic features; descriptive statistics were calculated and relationships among the above variables were assessed. Results: Most lesions were pigmented (71.7%), located on the lower extremities (43.3%), more frequent in the first decade (55.8%) and in females (57.9%). The nonpigmented type was more frequent in the head or neck region, whereas the pigmented types were more frequent on the lower extremities. Besides, these types showed different histopathologic features: the spindle cells usually predominated in the flat pigmented type, whereas dome-shaped types were usually composed of both spindle and epithelioid cells. Conclusions: In our patients, the pigmented Spitz nevi were more common than the nonpigmented ones; furthermore pigmented and nonpigmented Spitz nevi showed different anatomical locations and different histopathologic features.
KW - Epithelioid cell nevus
KW - Spindle cell nevus
KW - Spitz nevus
UR - http://www.scopus.com/inward/record.url?scp=0031013845&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031013845&partnerID=8YFLogxK
M3 - Article
C2 - 9031786
AN - SCOPUS:0031013845
VL - 194
SP - 20
EP - 25
JO - Dermatology
JF - Dermatology
SN - 1018-8665
IS - 1
ER -