Clinical role of blood levels

R. Latini, M. Bonati, G. Tognoni

Research output: Contribution to journalArticlepeer-review


The impact of drug level monitoring on practice and quality of therapy is discussed. Analysis of the literature and a more detailed discussion of three model drugs (salicylates, digoxin, and theophylline) show a surprisingly low degree of attention to the problem of evaluating the clinical relevance of a drug monitoring program through controlled studies and techniques. There is a potential, and possibly already existing, gap between clinical pharmacokinetics and routine therapy. Closer assessment of these points, with emphasis on educational programs, should be considered among the frontiers leading to a better integration of therapeutic monitoring into medical practice.

Original languageEnglish
Pages (from-to)3-9
Number of pages7
JournalTherapeutic Drug Monitoring
Issue number1
Publication statusPublished - 1980


  • Blood levels
  • Clinical efficacy
  • Controlled trials
  • Digoxin
  • Drug epidemiology
  • Salicylates
  • Theophylline
  • Therapeutic monitoring

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Health, Toxicology and Mutagenesis
  • Public Health, Environmental and Occupational Health
  • Toxicology


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