Analisi clinica e SEEG del comportamento critico di locomozione

Translated title of the contribution: Clinical-SEEG analysis of ictal locomotor behaviour

E. Gardella, S. Francione, L. Tassi, G. Rubboli, L. Castana, L. Nobili, G. Cantalupo, G. Lo Russo, C. A. Tassinari

Research output: Contribution to journalArticle

Abstract

Purpose: We compared clinical-EEG/SEEG features of bipedal/locomotor behaviour (LB), in frontal versus temporal lobe seizures (FLS, TLS). Method: Out of 87 consecutive candidates to epilepsy surgery, we selected 9 patients (5 temporal/4 frontal lobe; 85 seizures) presenting the anamnestic datum of ictal LB. Five patients underwent SEEG investigation (72 seizures) and 7 had a good outcome after epilepsy surgery The evaluation of bipedal/LB included clinical-kinematic analysis (Videopoint computerised system) and clinical-EEG/SEEG correlations analysis. Results: We observed clinical-kinematic differences between bipedal/LB of FLS and TLS, in terms of latency (respectively 9.7 versus 19.8 seconds) and/or features (faster and/or asymmetrical in TLS). In all patients the ictal discharge was lateralised in the non dominant hemisphere and the symptomatogenic zone, during bipedal manifestations, involved an extended fronto-mesial area including the gyrus cinguli. In one standing patient the stimulation of the fronto-lateral region, spreading to the mesial one, elicited a forward-backward LB. Conclusion: LB is quite specifically related to seizures arising from the non dominant hemisphere and reflects the activation of a widespread fronto-mesial circuit. From the semiological point of view, it is possible to differentiate LB in FLS and TLS. Human locomotion is an innate motor behaviour, which can involuntary occur from release of the physiologic spinal generator, in epileptic seizures or parasomnias (1). This is the first description of the possible relationships between cerebral activity and the lower generator for human locomotion.

Original languageItalian
Pages (from-to)81-83
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number136-137
Publication statusPublished - May 2008

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Stroke
Seizures
Epilepsy
Locomotion
Biomechanical Phenomena
Electroencephalography
Parasomnias
Instinct
Patient Discharge
Gyrus Cinguli
Frontal Lobe
Temporal Lobe

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Gardella, E., Francione, S., Tassi, L., Rubboli, G., Castana, L., Nobili, L., ... Tassinari, C. A. (2008). Analisi clinica e SEEG del comportamento critico di locomozione. Bollettino - Lega Italiana contro l'Epilessia, (136-137), 81-83.

Analisi clinica e SEEG del comportamento critico di locomozione. / Gardella, E.; Francione, S.; Tassi, L.; Rubboli, G.; Castana, L.; Nobili, L.; Cantalupo, G.; Lo Russo, G.; Tassinari, C. A.

In: Bollettino - Lega Italiana contro l'Epilessia, No. 136-137, 05.2008, p. 81-83.

Research output: Contribution to journalArticle

Gardella, E, Francione, S, Tassi, L, Rubboli, G, Castana, L, Nobili, L, Cantalupo, G, Lo Russo, G & Tassinari, CA 2008, 'Analisi clinica e SEEG del comportamento critico di locomozione', Bollettino - Lega Italiana contro l'Epilessia, no. 136-137, pp. 81-83.
Gardella E, Francione S, Tassi L, Rubboli G, Castana L, Nobili L et al. Analisi clinica e SEEG del comportamento critico di locomozione. Bollettino - Lega Italiana contro l'Epilessia. 2008 May;(136-137):81-83.
Gardella, E. ; Francione, S. ; Tassi, L. ; Rubboli, G. ; Castana, L. ; Nobili, L. ; Cantalupo, G. ; Lo Russo, G. ; Tassinari, C. A. / Analisi clinica e SEEG del comportamento critico di locomozione. In: Bollettino - Lega Italiana contro l'Epilessia. 2008 ; No. 136-137. pp. 81-83.
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AU - Castana, L.

AU - Nobili, L.

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AU - Lo Russo, G.

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