L'impiego clinico dei tests al lattice. II. Valutazione dei metodi al lattice per la determinazione della proteina C reattiva (PCR).

Translated title of the contribution: Clinical use of latex tests. II. Evaluation of latex tests in C-reactive protein determination

R. Bonamore, M. C. Garlaschi, M. L. Garlaschi, F. Varotto

Research output: Contribution to journalArticle

Abstract

We compared the most reliable and practical laboratory methods for the quantitative determination of serum C-reactive protein that is polistyrene latex particles together with purified anti-C-reactive protein rabbit globulin, the precipitation test using anti-C-reactive protein serum and finally, radial immunodiffusion on agar-gel plates. We examined 163 serum specimens from ambulatory patients and from various hospitalized patients in Istituti Clinici di Perfezionamento of Milan (Italy). All the methods tested showed a good qualitative discrimination for serum C-reactive protein presence or absence at pathological levels. We also compared the two latex methods. In conclusion, radial immunodiffusion confirmed to be the best method for accurate C-reactive protein dosage during inflammatory and degenerative processes.

Original languageItalian
Pages (from-to)166-174
Number of pages9
JournalQuaderni Sclavo di diagnostica clinica e di laboratorio
Volume18
Issue number2
Publication statusPublished - Jun 1982

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Latex
C-Reactive Protein
Immunodiffusion
Blood Proteins
Globulins
Serum
Microspheres
Italy
Agar
Gels
Rabbits

ASJC Scopus subject areas

  • Medicine(all)

Cite this

L'impiego clinico dei tests al lattice. II. Valutazione dei metodi al lattice per la determinazione della proteina C reattiva (PCR). / Bonamore, R.; Garlaschi, M. C.; Garlaschi, M. L.; Varotto, F.

In: Quaderni Sclavo di diagnostica clinica e di laboratorio, Vol. 18, No. 2, 06.1982, p. 166-174.

Research output: Contribution to journalArticle

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