Clinicopathologic and molecular features of Hodgkin's lymphoma

Anas Younes, Antonino Carbone

Research output: Contribution to journalArticlepeer-review


Hodgkin's lymphoma is a relatively uncommon malignancy that predominantly effects young adults. It became the first human cancer to be cured with combination chemotherapy. Unfortunately, many cured patients do not live their expected lifespan because of long-term lethal effects of therapy. Novel treatment strategies based on our understanding of Hodgkin's lymphoma biology are currently being explored to maintain the high cure rate without the added treatment related toxicity.

Original languageEnglish
Pages (from-to)500-507
Number of pages8
JournalCancer Biology and Therapy
Issue number5
Publication statusPublished - Sep 2003


  • CD30
  • CD40
  • Cytokines
  • ERK
  • NF-κB
  • RANK
  • Reed-Sternberg
  • Rituximab

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Molecular Medicine
  • Pharmacology


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