Clobazam in drug-resistant and alcoholic withdrawal seizures

M. Franceschi, L. Ferini-Strambi, M. Mastrangelo, S. Smirne

Research output: Contribution to journalArticlepeer-review

Abstract

Clobazam, which has been reported to posess distinct and prompt, but transient, anticonvulsant properties in almost all varieties of epilepsy, was used with other anti-epileptic drugs in drug-resistant temporal lobe epilepsy and Lennox-Gastaut syndrome, and as single drug in the prophylaxis of alcoholic withdrawal seizures. The satisfactory findings confirm the outstanding and rapid anticonvulsant properties of clobazam. In this study, side-effects and exhaustion of anticonvulsant properties did not present important problems. It is concluded that clobazam is of value in alcoholic withdrawal syndrome, both for its prompt anticonvulsant properties and for its sedative action.

Original languageEnglish
Pages (from-to)119-125
Number of pages7
JournalClinical Trials Journal
Volume20
Issue number3
Publication statusPublished - 1983

Keywords

  • alcoholic withdrawal seizures
  • anti-epileptic drugs
  • Clobazam
  • drug-resistant epilepsies

ASJC Scopus subject areas

  • Pharmacology (medical)

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