TY - JOUR
T1 - Clodronate and hydroxychloroquine in erosive osteoarthritis
T2 - A 24-month open randomized pilot study
AU - Saviola, Gianantonio
AU - Abdi-Ali, Lul
AU - Campostrini, Lorella
AU - Sacco, Silvano
AU - Baiardi, Paola
AU - Manfredi, Mariangela
AU - Mannoni, Alessandro
AU - Benucci, Maurizio
PY - 2012/4
Y1 - 2012/4
N2 - We evaluated the efficacy of clodronate for treating active erosive osteoarthritis of the hand and to compare it with hydroxychloroquine. Group A consisted of 24 patients treated for 24 months with clodronate 300 mg i.v. for 7 days followed by clodronate i.m. 100 mg for 14 days every 3 months. Group B comprised 14 patients treated with hydroxychloroquine 400 mg daily for 30 days followed by 200 mg daily for the next 11 months. In group A 21/24 patients completed the trial and obtained significant pain reduction (p
AB - We evaluated the efficacy of clodronate for treating active erosive osteoarthritis of the hand and to compare it with hydroxychloroquine. Group A consisted of 24 patients treated for 24 months with clodronate 300 mg i.v. for 7 days followed by clodronate i.m. 100 mg for 14 days every 3 months. Group B comprised 14 patients treated with hydroxychloroquine 400 mg daily for 30 days followed by 200 mg daily for the next 11 months. In group A 21/24 patients completed the trial and obtained significant pain reduction (p
KW - Clodronate
KW - Erosive osteoarthritis of the hand
KW - Hydroxychloroquine
UR - http://www.scopus.com/inward/record.url?scp=84861478455&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861478455&partnerID=8YFLogxK
U2 - 10.1007/s10165-011-0506-8
DO - 10.1007/s10165-011-0506-8
M3 - Article
C2 - 21853386
AN - SCOPUS:84861478455
VL - 22
SP - 256
EP - 263
JO - Modern Rheumatology
JF - Modern Rheumatology
SN - 1439-7595
IS - 2
ER -