Abstract
T lymphocytes were isolated from tumor biopsies in 13 patients with breast carcinomas. Immunohistology with monoclonal antibodies confirmed the presence of mononuclear cell infiltrates composed primarily of T lymphocytes in all tumors studied. While the proportion of T lymphocytes expressing the T4 or the T8 surface marker varied from tumor to tumor as determined by morphometric analysis, T8+ cells were more numerous than T4+ cells in 8/12 breast tumors studied. Relatively few T cells (
| Original language | English |
|---|---|
| Pages (from-to) | 169-178 |
| Number of pages | 10 |
| Journal | Cancer Immunology, Immunotherapy |
| Volume | 23 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Dec 1986 |
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ASJC Scopus subject areas
- Oncology
- Immunology
- Cancer Research
Cite this
Clonal analysis and in situ characterization of lymphocytes infiltrating human breast carcinomas. / Whiteside, Theresa L.; Miescher, Sylvia; Hurlimann, Jean; Moretta, Lorenzo; von Fliedner, Vladimir.
In: Cancer Immunology, Immunotherapy, Vol. 23, No. 3, 12.1986, p. 169-178.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clonal analysis and in situ characterization of lymphocytes infiltrating human breast carcinomas
AU - Whiteside, Theresa L.
AU - Miescher, Sylvia
AU - Hurlimann, Jean
AU - Moretta, Lorenzo
AU - von Fliedner, Vladimir
PY - 1986/12
Y1 - 1986/12
N2 - T lymphocytes were isolated from tumor biopsies in 13 patients with breast carcinomas. Immunohistology with monoclonal antibodies confirmed the presence of mononuclear cell infiltrates composed primarily of T lymphocytes in all tumors studied. While the proportion of T lymphocytes expressing the T4 or the T8 surface marker varied from tumor to tumor as determined by morphometric analysis, T8+ cells were more numerous than T4+ cells in 8/12 breast tumors studied. Relatively few T cells (
AB - T lymphocytes were isolated from tumor biopsies in 13 patients with breast carcinomas. Immunohistology with monoclonal antibodies confirmed the presence of mononuclear cell infiltrates composed primarily of T lymphocytes in all tumors studied. While the proportion of T lymphocytes expressing the T4 or the T8 surface marker varied from tumor to tumor as determined by morphometric analysis, T8+ cells were more numerous than T4+ cells in 8/12 breast tumors studied. Relatively few T cells (
UR - http://www.scopus.com/inward/record.url?scp=0022963713&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022963713&partnerID=8YFLogxK
U2 - 10.1007/BF00205646
DO - 10.1007/BF00205646
M3 - Article
C2 - 3024832
AN - SCOPUS:0022963713
VL - 23
SP - 169
EP - 178
JO - Cancer Immunology and Immunotherapy
JF - Cancer Immunology and Immunotherapy
SN - 0340-7004
IS - 3
ER -