Clonal B-cell lymphocytosis: A new member?

Maurilio Ponzoni, Paolo Ghia

Research output: Contribution to journalArticlepeer-review


In this issue of Blood, Xochelli et al have identified, in otherwise healthy individuals with no clinical signs of lymphoproliferative disorders, a circulating clonal B-cell population with an immunophenotype consistent with a marginal zone B-cell population (CBL-MZ).1 This scenario is reminiscent of monoclonal B-cell lymphocytosis (MBL)2 of the "CD5-negative type," although the report includes cases with rather prominent B lymphocytosis (up to 34 × 109/L, K. Stamatopoulos, Institute of Applied Biosciences, Thessaloniki, Greece, written communication, December 16, 2013), being above the MBL threshold of 5 × 109 B lymphocytes/L2.

Original languageEnglish
Pages (from-to)1118-1119
Number of pages2
Issue number8
Publication statusPublished - Feb 20 2014

ASJC Scopus subject areas

  • Hematology
  • Biochemistry
  • Cell Biology
  • Immunology


Dive into the research topics of 'Clonal B-cell lymphocytosis: A new member?'. Together they form a unique fingerprint.

Cite this